Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CFD | P00746 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17953132 | 0.81 | KDM4E (0.55) | KDM4EALDH1A1CYP2C19USP2HPGD | |
| SCHEMBL132968 | 0.80 | MRGPRX4 (0.47) | KDM4EALDH1A1CYP2C19USP2HPGD | |
| SCHEMBL4186655 | 0.80 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL31738417 | 0.80 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL6703981 | 0.78 | CYP3A4 (0.44) | KDM4EALDH1A1MAPTTSHRGAA | |
| SCHEMBL21807289 | 0.78 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL11464187 | 0.78 | SRC (0.47) | KDM4EALDH1A1TSHRGAARAB9A | |
| SCHEMBL3437173 | 0.78 | KDM4E (0.53) | KDM4EALDH1A1MAPTTSHRGAA | |
| SCHEMBL11229207 | 0.78 | APEX1 (0.50) | KDM4EALDH1A1CYP2C19USP2HPGD | |
| SCHEMBL27559288 | 0.78 | MAPT (0.43) | KDM4EALDH1A1CYP2C19HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229348-A | Penicillanic acid derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1980-10-21 | — | — | US | disclosed |