Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9003751 | 0.85 | POLB (0.39) | MEN1USP2ALDH1A1MAPTHPGD | |
| SCHEMBL24612205 | 0.79 | ALDH1A1 (0.40) | MEN1USP2ALDH1A1MAPTHPGD | |
| SCHEMBL10154430 | 0.78 | DPP4 (0.33) | FFAR1 | |
| SCHEMBL22311215 | 0.77 | LPL (0.35) | HPGDTSHRHTTHSD17B10 | |
| SCHEMBL9481855 | 0.71 | — | — | |
| SCHEMBL10175255 | 0.70 | ALDH1A1 (0.36) | USP2ALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL17914320 | 0.69 | MAPT (0.42) | MEN1USP2ALDH1A1MAPTHPGD | |
| SCHEMBL18626758 | 0.69 | MAPT (0.44) | MEN1USP2ALDH1A1MAPTHPGD | |
| SCHEMBL147077 | 0.69 | — | — | |
| SCHEMBL9049427 | 0.68 | MAPT (0.41) | MEN1USP2ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4187230-A | Preparation of 5-aroyl-pyrrole compounds | ETHYL CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |