Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 9/20 | 0.54 |
| ▸ | HTT | P42858 | 5/20 | 0.54 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11455980 | 0.89 | LMNA (0.56) | LMNAHTTSTING1CYP1A2CYP2C19 | |
| SCHEMBL11447908 | 0.88 | STING1 (0.52) | LMNAHTTSTING1CYP1A2CYP2C19 | |
| SCHEMBL11407300 | 0.84 | LMNA (0.56) | LMNAHTTSTING1CYP1A2CYP2C19 | |
| SCHEMBL13113103 | 0.81 | LMNA (0.64) | LMNAHTTSTING1GAANFKB1 | |
| SCHEMBL12261479 | 0.78 | LMNA (0.53) | LMNAHTTSTING1GAANFKB1 | |
| SCHEMBL11790220 | 0.77 | LMNA (0.51) | LMNAHTTSTING1GAANFKB1 | |
| Nifurmerone SCHEMBL398798 | 0.77 | LMNA (0.51) | LMNAHTTSTING1GAANFKB1 | |
| SCHEMBL13753324 | 0.76 | LMNA (0.71) | LMNAHTTSTING1GAANFKB1 | |
| SCHEMBL12217640 | 0.75 | HPGD (0.50) | HTTNPC1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL6734715 | 0.74 | MAPT (0.60) | LMNAHTTCYP1A2CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224448-A | FUNGICIDES, BACTERICIDES | HABER RAPHAEL R G | 1980-09-23 | — | — | US | disclosed |
| US-4087427-A | BACTERICIDES, FUNGICIDES | HABER RAPHAEL RALPH GEORGE | 1978-05-02 | — | — | US | disclosed |