Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 7/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11407927 | 0.83 | LMNA (0.56) | MAPTLMNAHTTGAANPC1 | |
| 5-Nitro-2-Furoic Acid SCHEMBL1221377 | 0.82 | LMNA (0.58) | LMNAHTTGAANPC1MITF | |
| SCHEMBL14489520 | 0.82 | MAPT (0.43) | MAPTLMNAHTTGAANPC1 | |
| SCHEMBL11455980 | 0.81 | LMNA (0.56) | MAPTLMNAHTTGAANPC1 | |
| SCHEMBL11407300 | 0.80 | LMNA (0.56) | MAPTLMNAHTTGAANPC1 | |
| Metofurone SCHEMBL687311 | 0.80 | RAB9A (0.54) | MAPTLMNAHTTGAANPC1 | |
| SCHEMBL1199803 | 0.80 | L3MBTL1 (0.55) | MAPTLMNAHTTGAANPC1 | |
| SCHEMBL6352334 | 0.80 | LMNA (0.53) | MAPTLMNAHTTGAANPC1 | |
| 5-Nitro-2-Furoic Acid SCHEMBL2115021 | 0.80 | LMNA (0.57) | LMNAHTTGAANPC1MITF | |
| SCHEMBL13101048 | 0.79 | LMNA (0.51) | MAPTLMNAHTTGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655203-B2 | Nitration | ETH ZURICH (CH) | 2023-05-23 | — | — | US | disclosed |
| US-11655203-B2 | Nitration | ETH ZURICH (CH) | 2023-05-23 | — | — | US | disclosed |
| US-11655203-B2 | Nitration | ETH ZURICH (CH) | 2023-05-23 | — | — | US | disclosed |
| US-20220009875-A1 | NITRATION | ETH ZURICH (CH) | 2022-01-13 | — | — | US | disclosed |
| US-20220009875-A1 | NITRATION | ETH ZURICH (CH) | 2022-01-13 | — | — | US | disclosed |
| CN-113302186-A | Nitration | 瑞士苏黎世联邦理工学院 | 2021-08-24 | — | — | CN | disclosed |
| EP-3717464-B1 | NITRATION | ETH ZUERICH (CH) | 2021-06-16 | — | — | EP | disclosed |
| EP-3717464-B1 | NITRATION | ETH ZUERICH (CH) | 2021-06-16 | — | — | EP | disclosed |
| EP-1921077-B1 | AGENT FOR TREATING AND/OR PREVENTING SLEEP DISORDER | KYOWA HAKKO KIRIN CO LTD (JP) | 2017-07-26 | — | — | EP | disclosed |
| US-20170014419-A1 | MEDICAMENT FOR SUPPRESSING MALIGNANT TUMOR METASTASIS | NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER (JP) | 2017-01-19 | — | — | US | disclosed |
| EP-1409464-A1 | OXAZOLIDINONE DERIVATIVES AS POTENTIAL ANTIMICROBIALS | RANBAXY LABORATORIES, LTD. (IN) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003008389-A1 | OXAZOLIDINONE DERIVATIVES AS POTENTIAL ANTIMICROBIALS | RANBAXY LABORATORIES LIMITED (IN) | 2003-01-30 | — | — | WO | disclosed |
| EP-0163854-B1 | PROCESS FOR THE ELIMINATION OF FLUORESCENCE AND CATIONIC OR AMPHOTERIC AROMATIC NITRO COMPOUNDS | BAYER AG (DE) | 1991-02-27 | — | — | EP | disclosed |
| US-4695405-A | Process for quenching fluorescence, and new cationic or amphoteric aromatic nitro compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-22 | — | — | US | disclosed |
| EP-0163854-A2 | Process for the elimination of fluorescence and cationic or amphoteric aromatic nitro compounds | BAYER AG (DE) | 1985-12-11 | — | — | EP | disclosed |
| US-4224448-A | FUNGICIDES, BACTERICIDES | HABER RAPHAEL R G | 1980-09-23 | — | — | US | disclosed |
| US-4093812-A | MICROBIOCIDES, DISINFECTANTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) | 1978-06-06 | — | — | US | disclosed |
| US-4087427-A | BACTERICIDES, FUNGICIDES | HABER RAPHAEL RALPH GEORGE | 1978-05-02 | — | — | US | disclosed |
| US-4072496-A | 2,6-Dichlorobenzaldehyde tetrahydro-2-furoyl hydrazone and its use as a ripener for sugarcane | W. R. GRACE & CO. (US) | 1978-02-07 | — | — | US | disclosed |
| US-3992186-A | INCREASING SUCROSE YIELD | HAWAIIAN SUGAR PLANTERS' ASSOCIATION (US) | 1976-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220009875-A1 | NITRATION | NOS1, NOS2, NOS3 | MAPT 3137/4885LMNA 4595/4885HTT 2753/4885 |
| US-20170014419-A1 | MEDICAMENT FOR SUPPRESSING MALIGNANT TUMOR METASTASIS | AGTR2, MME, AGTR1 | MAPT 4456/4885LMNA 4159/4885HTT 4790/4885 |
| US-11655203-B2 | Nitration | NOS1, NOS2, NOS3 | MAPT 3137/4885LMNA 4595/4885HTT 2753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.