Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11449189 | 0.81 | CPB2 (0.43) | CPB2MMEALDH1A1CYP2C19ACE | |
| Hydrochloric Acid SCHEMBL11458250 | 0.79 | CPB2 (0.42) | CPB2MMECYP2C19ACEPOLB | |
| SCHEMBL10549886 | 0.78 | CPB2 (0.44) | CPB2MMEALDH1A1CYP2C19ACE | |
| SCHEMBL5295104 | 0.76 | MME (0.44) | MMEACE | |
| SCHEMBL9743096 | 0.76 | MME (0.44) | MMEACE | |
| SCHEMBL607225 | 0.76 | MME (0.44) | MMEACE | |
| SCHEMBL11450760 | 0.74 | CPB2 (0.34) | CPB2MMEALDH1A1CYP2C19ACE | |
| SCHEMBL11209747 | 0.74 | — | — | |
| SCHEMBL11214854 | 0.73 | CPB2 (0.37) | CPB2MMEALDH1A1CYP2C19ACE | |
| SCHEMBL7341626 | 0.73 | CPB2 (0.41) | CPB2MMEALDH1A1CYP2C19ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4241076-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1980-12-23 | — | — | US | disclosed |