SCHEMBL607225

SCHEMBL607225

CC(=O)SC[C@@H](C)C(=O)Cl

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MME P08473 2/20 0.44
ACE P12821 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5295104 1.00 MME (0.44) MMEACE
SCHEMBL9743096 1.00 MME (0.44) MMEACE
Benzene SCHEMBL10568712 0.94 ACE (0.53) MMEACE
SCHEMBL11268067 0.82 MME (0.42) MMEACE
SCHEMBL10567567 0.81 ACE (0.47) MMEACE
SCHEMBL11274627 0.79 ALDH1A1 (0.37)
SCHEMBL10549886 0.78 CPB2 (0.44) MMEACE
SCHEMBL342981 0.78 MME (0.50) MMEACE
SCHEMBL2314507 0.78 MME (0.50) MMEACE
SCHEMBL6227437 0.78 MME (0.50) MMEACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111721879-B Method for detecting D-3-acetylmercapto-2-methylpropionyl chloride in captopril by gas chromatography-mass spectrometry 南京林业大学 2024-11-22 CN claimed
CN-111721879-A Method for detecting D-3-acetylmercapto-2-methylpropanoyl chloride in captopril by gas chromatography-mass spectrometry 南京林业大学 2020-09-29 CN claimed
US-20120041225-A1 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF VAIDYA NITEEN A (US) 2012-02-16 US claimed
CN-102351768-A Method for synthesizing captopril and ceptopril UNIV ZHEJIANG TECHNOLOGY 2012-02-15 CN claimed
EP-1981831-A2 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF Vaidya, Niteen A. (US) 2008-10-22 EP claimed
WO-2007092264-A2 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF VAIDYA NITEEN A (US) 2007-08-16 WO claimed
US-20070185346-A1 Kit for automated resolving agent selection and method thereof VAIDYA NITEEN A 2007-08-09 US claimed
US-5387697-A Process for the preparation of 1-[3-acetylthio-2(s)-methylpropanoyl]-l-proline MERCK & CO., INC. (US) 1995-02-07 US claimed
CN-111721879-B Method for detecting D-3-acetylmercapto-2-methylpropionyl chloride in captopril by gas chromatography-mass spectrometry 南京林业大学 2024-11-22 CN disclosed
CN-111721879-B Method for detecting D-3-acetylmercapto-2-methylpropionyl chloride in captopril by gas chromatography-mass spectrometry 南京林业大学 2024-11-22 CN disclosed
CN-111721879-B Method for detecting D-3-acetylmercapto-2-methylpropionyl chloride in captopril by gas chromatography-mass spectrometry 南京林业大学 2024-11-22 CN disclosed
CN-111721879-A Method for detecting D-3-acetylmercapto-2-methylpropanoyl chloride in captopril by gas chromatography-mass spectrometry 南京林业大学 2020-09-29 CN disclosed
CN-111721879-A Method for detecting D-3-acetylmercapto-2-methylpropanoyl chloride in captopril by gas chromatography-mass spectrometry 南京林业大学 2020-09-29 CN disclosed
CN-111721879-A Method for detecting D-3-acetylmercapto-2-methylpropanoyl chloride in captopril by gas chromatography-mass spectrometry 南京林业大学 2020-09-29 CN disclosed
US-5387697-A Process for the preparation of 1-[3-acetylthio-2(s)-methylpropanoyl]-l-proline MERCK & CO., INC. (US) 1995-02-07 US disclosed
US-5387697-A Process for the preparation of 1-[3-acetylthio-2(s)-methylpropanoyl]-l-proline MERCK & CO., INC. (US) 1995-02-07 US disclosed
EP-0384636-A1 Pharmaceutically active compounds FISONS plc (GB) 1990-08-29 EP disclosed
EP-0086453-B1 THIAZASPIRO DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION LUITPOLD-WERK Chemisch-pharmazeutische Fabrik GmbH & Co. (DE) 1988-09-28 EP disclosed
US-4587250-A HYPOTENSIVE AGENTS LUITPOLD-WERK CHEMISCHPHARMAZEUTISCHE FABRIK GMBH & CO. (DE) 1986-05-06 US disclosed
EP-0086453-A2 Thiazaspiro derivatives, process for their preparation and pharmaceutical composition LUITPOLD-WERK Chemisch-pharmazeutische Fabrik GmbH & Co. (DE) 1983-08-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120041225-A1 KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF ACKR3, KIT, C3AR1 MME 896/4885ACE 140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.