Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 6/20 | 0.53 |
| ▸ | FABP2 | P12104 | 2/20 | 0.53 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135713 | 0.90 | PPARA (0.72) | PPARACYP1A2CYP3A4MEN1MAPT | |
| SCHEMBL3811479 | 0.87 | PPARA (0.81) | PPARACYP1A2CYP3A4MEN1MAPT | |
| SCHEMBL11471320 | 0.86 | PPARA (0.58) | PPARACYP1A2CYP3A4MEN1MAPT | |
| SCHEMBL11537290 | 0.85 | PPARA (0.66) | PPARACYP1A2CYP3A4MEN1MAPT | |
| SCHEMBL11478612 | 0.83 | OPRK1 (0.73) | PPARACYP1A2CYP3A4MEN1MAPT | |
| SCHEMBL822492 | 0.82 | PPARA (0.77) | PPARACYP1A2CYP3A4MEN1MAPT | |
| SCHEMBL11074943 | 0.82 | PPARA (0.86) | PPARACYP1A2CYP3A4MEN1MAPT | |
| SCHEMBL11639698 | 0.81 | OPRK1 (0.62) | PPARACYP1A2CYP3A4MEN1MAPT | |
| SCHEMBL31742332 | 0.81 | CNR1 (0.73) | PPARACYP1A2CYP3A4MEN1MAPT | |
| SCHEMBL11539959 | 0.81 | PPARA (0.60) | PPARACYP1A2CYP3A4MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4182902-A | P-(P'-CHLOROBENZYL) PHENOXYACETIC ACID | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1980-01-08 | — | — | US | disclosed |
| US-4153803-A | Cholesterol-lowering phenoxyalkanoic acid esters | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1979-05-08 | — | — | US | disclosed |