Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633028 | 0.86 | LMNA (0.61) | LMNATDP1F2MAPK1HIF1A | |
| SCHEMBL19139254 | 0.86 | LMNA (0.61) | LMNATDP1F2MAPK1HIF1A | |
| SCHEMBL27316107 | 0.85 | TDP1 (0.50) | LMNATDP1KMT2ATSHRSMN1; SMN2 | |
| Propene SCHEMBL4012587 | 0.83 | LMNA (0.67) | LMNATDP1F2MAPK1HIF1A | |
| SCHEMBL2844201 | 0.83 | TDP1 (0.66) | LMNATDP1F2MAPK1HIF1A | |
| Propene SCHEMBL6062789 | 0.83 | LMNA (0.67) | LMNATDP1F2MAPK1HIF1A | |
| Propene SCHEMBL4455281 | 0.83 | LMNA (0.67) | LMNATDP1F2MAPK1HIF1A | |
| Propene SCHEMBL6431713 | 0.83 | LMNA (0.67) | LMNATDP1F2MAPK1HIF1A | |
| SCHEMBL15578959 | 0.82 | LMNA (0.66) | LMNATDP1F2MAPK1HIF1A | |
| SCHEMBL21104603 | 0.82 | LMNA (0.61) | LMNATDP1F2MAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4211696-A | Disperse monoazo dyestuffs derived from 3,5-dinitro-2-amino thiophene as disazo component and an arylamine coupling component | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-07-08 | — | — | US | disclosed |