Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297778 | 0.91 | TDP1 (0.75) | TDP1LMNAALDH1A1F2MAPK1 | |
| SCHEMBL15309020 | 0.90 | ESR1 (0.50) | TDP1LMNAALDH1A1MAPK1SLC6A2 | |
| SCHEMBL9329294 | 0.89 | TDP1 (0.79) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL1151086 | 0.87 | TDP1 (0.76) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL6821599 | 0.87 | TDP1 (0.76) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| Fluorobenzene SCHEMBL27336092 | 0.85 | TDP1 (0.49) | TDP1LMNAALDH1A1F2MAPK1 | |
| SCHEMBL137486 | 0.83 | TDP1 (0.83) | TDP1LMNAALDH1A1F2MAPK1 | |
| SCHEMBL25305081 | 0.83 | TDP1 (0.69) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL11518351 | 0.83 | TDP1 (0.63) | TDP1LMNAALDH1A1F2MAPK1 | |
| SCHEMBL30354555 | 0.83 | TDP1 (0.63) | TDP1LMNAALDH1A1F2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5329016-A | Antianxiety, hypnotic agents, antiepileptic agents or nootropics | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-07-12 | — | — | US | claimed |
| US-5175162-A | Anxiolytic, antiepilepic agents | YOSHITIOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1992-12-29 | — | — | US | claimed |
| EP-4045088-A1 | METHOD FOR THE PREPARATION OF POLYMERIC CARRIERS FOR PH- CONTROLLED DRUG RELEASE AND THEIR CONJUGATES WITH DRUGS | Ustav Makromolekularni Chemie AV CR, v.v.i. (CZ) | 2022-08-24 | — | — | EP | disclosed |
| US-9242955-B2 | Synthesis of cyclic carbonates | UNIVERSITY OF YORK (GB) | 2016-01-26 | — | — | US | disclosed |
| CN-102666461-B | Ring compound, its production method, radiation-ray sensitive composition and corrosion-resisting pattern formation method | MITSUBISHI GAS CHEMICAL CO.,INC. (JP) | 2015-09-30 | — | — | CN | disclosed |
| CN-101679343-B | Synthesis of cyclic carbonates in the presence of dimeric aluminium (salen) catalysts | UNIV NEWCASTLE | 2014-06-18 | — | — | CN | disclosed |
| CN-103804211-A | Synthetic method of 4-(acetyl amino)-2-hydroxy-3-(2-carbonyl ethyl) methyl benzoate | TIANJIN WEIJIE TECHNOLOGY CO LTD | 2014-05-21 | — | — | CN | disclosed |
| EP-2146977-B1 | SYNTHESIS OF CYCLIC CARBONATES IN THE PRESENCE OF DIMERIC ALUMINIUM (SALEN) CATALYSTS | UNIV NEWCASTLE (GB) | 2012-11-14 | — | — | EP | disclosed |
| CN-102766254-A | Method for producing liquid crystal polyester | SUMITOMO CHEMICAL CO | 2012-11-07 | — | — | CN | disclosed |
| CN-102731751-A | Method for producing liquid crystal polyester | SUMITOMO CHEMICAL CO | 2012-10-17 | — | — | CN | disclosed |
| CN-101035772-B | 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE) | JANSSEN PHARMACEUTICA N.V. (BE) | 2011-12-14 | — | — | CN | disclosed |
| US-5329016-A | Antianxiety, hypnotic agents, antiepileptic agents or nootropics | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0601184-A1 | FUSED PYRIDAZINE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994011398-A1 | CYCLIC COMPOUNDS LINKED BY A HETEROCYCLIC RING USEFUL AS INHIBITORS OF PLATELET GLYCOPROTEIN IIb/IIIa | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-05-26 | — | — | WO | disclosed |
| EP-0596125-A1 | CONDENSED THIOPHENE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5175162-A | Anxiolytic, antiepilepic agents | YOSHITIOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1992-12-29 | — | — | US | disclosed |
| US-5081287-A | Pesticidal polyhalo alkenoic acid esters | FMC CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0465254-A1 | Fused thiophene compounds and uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-01-08 | — | — | EP | disclosed |
| EP-0426018-A2 | Thiophene compounds and their pharmaceutical uses | YOSHITIOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |
| US-4950666-A | INSECTS, ACARIDS, AND NEMATODES | FMC CORPORATION (US) | 1990-08-21 | — | — | US | disclosed |