Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | INMT | O95050 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11459141 | 1.00 | GRM5 (0.45) | GRM5INMTALDH1A1KDM4EALOX15 | |
| SCHEMBL11460317 | 0.84 | GRM5 (0.45) | GRM5INMTALDH1A1KDM4EALOX15 | |
| SCHEMBL11460318 | 0.84 | GRM5 (0.45) | GRM5INMTALDH1A1KDM4EALOX15 | |
| SCHEMBL11479756 | 0.83 | GRM5 (0.42) | GRM5INMTALDH1A1KDM4EALOX15 | |
| SCHEMBL11476475 | 0.81 | GRM5 (0.43) | GRM5INMTALDH1A1KDM4EALOX15 | |
| SCHEMBL11476478 | 0.81 | GRM5 (0.43) | GRM5INMTALDH1A1KDM4EALOX15 | |
| SCHEMBL12753020 | 0.80 | GRM5 (0.47) | GRM5INMTALDH1A1KDM4EALOX15 | |
| SCHEMBL17813793 | 0.77 | GRM5 (0.55) | GRM5INMTALDH1A1KDM4EALOX15 | |
| SCHEMBL11233767 | 0.68 | GRM5 (0.73) | GRM5ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL11233774 | 0.68 | GRM5 (0.73) | GRM5ALDH1A1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4181661-A | SCHIZOPHRENIA, PSYCHOLOGICAL DISORDERS | MERCK & CO., INC. (US) | 1980-01-01 | — | — | US | disclosed |