Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.73 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233767 | 1.00 | GRM5 (0.73) | GRM5RAB9ANPC1KDM4EPOLB | |
| SCHEMBL11086248 | 0.83 | GRM5 (0.52) | GRM5RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL11086245 | 0.83 | GRM5 (0.52) | GRM5RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL10993126 | 0.81 | GRM5 (0.62) | GRM5RAB9ANPC1KDM4EPOLB | |
| SCHEMBL10993124 | 0.81 | GRM5 (0.62) | GRM5RAB9ANPC1KDM4EPOLB | |
| SCHEMBL10989017 | 0.80 | GRM5 (0.68) | GRM5RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL10989034 | 0.80 | GRM5 (0.68) | GRM5RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL10996908 | 0.80 | GRM5 (0.61) | GRM5RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL10996903 | 0.80 | GRM5 (0.61) | GRM5RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL10989729 | 0.80 | GRM5 (0.61) | GRM5RAB9ANPC1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57171986-A | — | — | None | — | — | JP | disclosed |
| JP-S57171986-A | HETEROCYLIC RING COMPOUND CONTAINING SULFUR | TAIHO YAKUHIN KOGYO KK | 1982-10-22 | — | — | JP | disclosed |