Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | INMT | O95050 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11476475 | 1.00 | GRM5 (0.43) | GRM5ALDH1A1INMTMEN1LMNA | |
| SCHEMBL11460318 | 0.86 | GRM5 (0.45) | GRM5ALDH1A1INMTMEN1LMNA | |
| SCHEMBL11460317 | 0.86 | GRM5 (0.45) | GRM5ALDH1A1INMTMEN1LMNA | |
| SCHEMBL11459141 | 0.81 | GRM5 (0.45) | GRM5ALDH1A1INMTMEN1LMNA | |
| SCHEMBL11459142 | 0.81 | GRM5 (0.45) | GRM5ALDH1A1INMTMEN1LMNA | |
| SCHEMBL12753020 | 0.78 | GRM5 (0.47) | GRM5ALDH1A1INMTMEN1LMNA | |
| SCHEMBL11479756 | 0.78 | GRM5 (0.42) | GRM5ALDH1A1INMTKDM4EALOX15 | |
| SCHEMBL17813793 | 0.75 | GRM5 (0.55) | GRM5ALDH1A1INMTMAPK1KDM4E | |
| SCHEMBL11466286 | 0.74 | GRM5 (0.38) | GRM5ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL11459994 | 0.69 | INMT (0.46) | GRM5ALDH1A1INMTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4181661-A | SCHIZOPHRENIA, PSYCHOLOGICAL DISORDERS | MERCK & CO., INC. (US) | 1980-01-01 | — | — | US | disclosed |