Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3202818 | 0.83 | KDM4E (0.40) | KDM4EPIK3CDNAAA | |
| SCHEMBL1222082 | 0.81 | KDM4E (0.35) | KDM4EPIK3CDNAAA | |
| SCHEMBL4952545 | 0.81 | PDE3B (0.40) | KDM4EPIK3CDNAAA | |
| SCHEMBL19123212 | 0.81 | KDM4E (0.35) | KDM4EPIK3CDNAAA | |
| SCHEMBL3101220 | 0.81 | KDM4E (0.35) | KDM4EPIK3CDNAAA | |
| SCHEMBL13158292 | 0.79 | KDM4E (0.38) | KDM4EPIK3CD | |
| SCHEMBL13158266 | 0.79 | KDM4E (0.34) | KDM4EPIK3CD | |
| Hydrochloric Acid SCHEMBL28199440 | 0.79 | KDM4E (0.34) | KDM4EPIK3CDNAAA | |
| SCHEMBL22242127 | 0.78 | PIK3CD (0.39) | KDM4EPIK3CDNAAA | |
| SCHEMBL6295124 | 0.78 | KMT2A (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293256-B2 | Sulfamide derivatives and cosmetic use thereof | L'OREAL (FR) | 2012-10-23 | — | — | US | disclosed |
| US-20110044918-A1 | Novel sulfamide derivatives and cosmetic use thereof | L'OREAL (FR) | 2011-02-24 | — | — | US | disclosed |
| US-7887824-B2 | such as N,N'-bis(2-hydroxyethyl)sulfamide; improved elasticity on stratum corneum | L'OREAL (FR) | 2011-02-15 | — | — | US | disclosed |
| US-20060134151-A1 | Novel sulfamide derivatives and cosmetic use thereof | L'OREAL (FR) | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110044918-A1 | Novel sulfamide derivatives and cosmetic use thereof | STS, TST, TPST2 | KDM4E 2705/4885PIK3CD 3122/4885CA12 2571/4885 |
| US-20060134151-A1 | Novel sulfamide derivatives and cosmetic use thereof | STS, TST, TPST2 | KDM4E 2705/4885PIK3CD 3122/4885CA12 2571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.