TPST2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL5708656	0.46	2/20
SCHEMBL29955707	0.42	2/20
SCHEMBL11541084	0.38	2/20
SCHEMBL28295389	0.38	2/20
SCHEMBL8171800	0.37	2/20
SCHEMBL29956932	0.36	2/20
SCHEMBL981569	0.35	2/20
SCHEMBL7026584	0.34	2/20
SCHEMBL28346097	0.34	2/20
SCHEMBL12416993	0.46	1/20
SCHEMBL12416977	0.46	1/20
SCHEMBL12416998	0.44	1/20
SCHEMBL27003687	0.43	1/20
SCHEMBL28262152	0.43	1/20
SCHEMBL29956402	0.43	1/20
SCHEMBL12416801	0.43	1/20

Clinical trials — most relevant to TPST2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
ALL SCTped FORUM - Pharmacogenomic Study (add-on Study)	PHASE4	UNKNOWN
A Trial of CM-AT in Children With Autism With All Levels of FCT (The Blum Study)	PHASE3	COMPLETED
A Phase II Study of TX Regimen as First-line Treatment for Asian Elderly Patients With Advanced Adenocarcinoma of Lung	PHASE2	COMPLETED
Sulforaphane in a New Jersey (NJ) Population of Individuals With Autism	PHASE2	ACTIVE_NOT_RECRUITING
Vaccine Treatment for Advanced Non-Small Cell Lung Cancer	PHASE1/PHASE2	COMPLETED
The Effect of Thyroid Hormone on Drug Elimination in Cancer Patients	PHASE2	COMPLETED
Variability of Sulfotransferase 1A1 Activity in Humans: an Approach to Improve Predictive Drug Response - Part I: Analysis of Intraindividual Variation in Healthy Adults	PHASE1	COMPLETED
2-Methoxyestradiol in Treating Patients With Advanced Solid Tumors	PHASE1	COMPLETED
Variability of Sulfotransferase Activity in Humans: an Approach to Improve Predictive Drug Response Part II: Analysis of Interindividual Variation in Hypertensive Patients	PHASE1	COMPLETED
Genetic Variants Associated With Adolescent Suicide Attempts	nan	COMPLETED
Biomarker for the Early Diagnosis and Monitoring in Tyrosinemia Type 1 (BioTyrosin)	nan	WITHDRAWN
Pharmacogenetic Determinants Of Treatment Response In Children	nan	RECRUITING
Chest Wall Deformities in Children - Epidemiological Data	nan	COMPLETED
Serum Basal Tryptase Levels in Healthy Children	nan	COMPLETED
Thermogenic Silencer Regulatory Factors in Humans	nan	ACTIVE_NOT_RECRUITING
Effect of Sulfur Amino Acid Depletion and Acetaminophen on Plasma Glutatione	nan	COMPLETED
Genome Environment Microbiome and Metabolome in Autism Study	nan	COMPLETED
A Pilot Study of Varying Doses of Tamoxifen in the Setting of Genetic Polymorphisms of CYP2D6	nan	COMPLETED
Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic Leukemia	nan	RECRUITING
Pharmacogenomic Response to Thyrotropin-Releasing Hormone Stimulation in Healthy Volunteers: The Influence of a Common Type 2 Deiodinase Genetic Polymorphism on Serum T3	nan	COMPLETED
Stem Cell Study of Genetics and Drug Addiction	nan	COMPLETED
Estrogen Receptor 1 Gene Polymorphism Frequency in Fibromyalgia Syndrome	nan	COMPLETED
Turner Syndrome: Genotype and Phenotype	nan	COMPLETED
Clinical Characterization of Frequent Monogenic Forms of Neurodevelopmental Disorders	nan	UNKNOWN
Molecular Epidemiology of Parkinson's Disease	nan	COMPLETED
APAP Hepatotoxicity After Therapeutic Doses	nan	UNKNOWN
Using Cotyledon Perfusion to Study Drugs Transfer Across the Placenta	nan	RECRUITING
Aromatase Inhibitor Clinical Trial	nan	UNKNOWN
Tamoxifen Pharmacogenetics in Asian Breast Cancer Women	nan	UNKNOWN
Individualized Antiretroviral Therapy	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a TPST2 binder may also engage these)

Protein	Name	Similarity
Q4R863	—	1.000	Q4R863 →
O88856	—	1.000	O88856 →
Q5RJS8	—	1.000	Q5RJS8 →
Q3SYY2	—	1.000	Q3SYY2 →
Q5ZJI0	—	1.000	Q5ZJI0 →
O70281	—	0.998	O70281 →
Q3KR92	—	0.996	Q3KR92 →
O60507	—	0.996	O60507 →
Q9PTE6	—	0.994	Q9PTE6 →
O77081	—	0.991	O77081 →
A2WYE9	—	0.987	A2WYE9 →
Q0JGK4	—	0.986	Q0JGK4 →
Q5BK26	—	0.985	Q5BK26 →
Q9VLA1	—	0.983	Q9VLA1 →
Q6ZV29	—	0.983	Q6ZV29 →
Q0VBN2	—	0.983	Q0VBN2 →
Q949Q1	—	0.983	Q949Q1 →
B3H5R0	—	0.982	B3H5R0 →
Q9SJ05	—	0.982	Q9SJ05 →
Q27675	—	0.982	Q27675 →
Q9LJK1	—	0.981	Q9LJK1 →
A4VCL2	—	0.981	A4VCL2 →
Q9VYB7	—	0.981	Q9VYB7 →
Q6H6N5	—	0.981	Q6H6N5 →
A8X181	—	0.981	A8X181 →
Q99M64	—	0.981	Q99M64 →
B4LQT7	—	0.981	B4LQT7 →
P31927	—	0.981	P31927 →
Q5B0V6	—	0.981	Q5B0V6 →
B4IL64	—	0.981	B4IL64 →