⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12678305 | 0.92 | — | — | |
| SCHEMBL15953782 | 0.79 | — | — | |
| SCHEMBL79191 | 0.77 | NOS2 (0.33) | — | |
| SCHEMBL5648243 | 0.77 | NOS2 (0.33) | — | |
| SCHEMBL15328487 | 0.72 | — | — | |
| SCHEMBL1146005 | 0.72 | — | — | |
| SCHEMBL4609280 | 0.72 | — | — | |
| SCHEMBL20601576 | 0.72 | — | — | |
| SCHEMBL10823486 | 0.72 | — | — | |
| SCHEMBL78700 | 0.70 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073373-A | Method for asymmetric synthesis of (R) -5' -methoxy labdanin | 广东嘉博制药有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-111004179-B | Resolution method of 5' -methoxylapatin | 武汉大安制药有限公司 | 2021-03-09 | — | — | CN | disclosed |
| CN-111004179-A | Resolution method of 5' -methoxylapatin | 武汉大安制药有限公司 | 2020-04-14 | — | — | CN | disclosed |
| CN-104334717-B | The dewaxing buffer solution of containing water-soluble organic solvent and its using method | 理查艾伦科学公司 | 2017-03-15 | — | — | CN | disclosed |
| CN-104380107-B | The method preparing biology sensor | 诺威奥森斯有限公司 | 2016-11-02 | — | — | CN | disclosed |
| CN-102782927-B | Nonaqueous electrolyte solution, electrochemical element using same, and 1,2-dioxypropane compound used in same | UBE INDUSTRIES | 2015-07-15 | — | — | CN | disclosed |
| CN-104380107-A | Process for making biosensor | NOVIOSENSE B V | 2015-02-25 | — | — | CN | disclosed |
| CN-104334717-A | Dewaxing buffer containing a water-soluble organic solvent and methods of use thereof | RICHARD ALLAN SCIENT COMPANY | 2015-02-04 | — | — | CN | disclosed |
| US-7888374-B2 | Inhibitors of c-jun N-terminal kinases | ABBOTT LABORATORIES (US) | 2011-02-15 | — | — | US | disclosed |
| WO-2006083673-A2 | PYRIDINE DERIVATIVES USEFUL AS INHIBITORS OF C-JUN N-TERMINAL KINASES | ABBOTT LABORATORIES (US) | 2006-08-10 | — | — | WO | disclosed |
| US-20060173050-A1 | Inhibitors of c-Jun N-terminal kinases | ABBVIE INC. | 2006-08-03 | — | — | US | disclosed |
| US-20050171132-A1 | Diaminopyrimidine derivatives as selective growth hormone secrectgogue receptor (GHS-R) antagonists | XIN ZHILI (US) | 2005-08-04 | — | — | US | disclosed |
| US-20050171131-A1 | Diaminopyrimidine derivatives as growth hormone secrectgogue receptor (GHS-R) antagonists | KOSOGOF CHRISTI (US) | 2005-08-04 | — | — | US | disclosed |
| WO-2005030734-A1 | DIAMINOPYRIMIDINE DERIVATIVES AS SELECTIVE GROWTH HORMONE SECRECTGOGUE RECEPTOR (GHS-R) ANTAGONISTS | ABBOTT LABORATORIES (US) | 2005-04-07 | — | — | WO | disclosed |
| US-20050070712-A1 | Pyrimidine derivatives as ghrelin receptor modulators | ABBOTT LABORATORIES | 2005-03-31 | — | — | US | disclosed |
| US-3970679-A | Process for the production of organotin halides in sulphones as reaction medium | CIBA-GEIGY CORPORATION (US) | 1976-07-20 | — | — | US | disclosed |