Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601261 | 0.73 | — | — | |
| SCHEMBL1146008 | 0.70 | — | — | |
| SCHEMBL9197226 | 0.65 | — | — | |
| SCHEMBL21727237 | 0.65 | KDM4E (0.46) | KDM4E | |
| SCHEMBL2904322 | 0.65 | KDM4E (0.46) | KDM4E | |
| SCHEMBL5481927 | 0.65 | — | — | |
| SCHEMBL11501519 | 0.65 | KDM4E (0.46) | KDM4E | |
| SCHEMBL15062108 | 0.65 | — | — | |
| SCHEMBL10268948 | 0.65 | KDM4E (0.46) | KDM4E | |
| SCHEMBL772885 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9873691-B2 | TRPV1 antagonists including dihydroxy substituent and uses thereof | PURDUE PHARMA L.P. (US) | 2018-01-23 | — | — | US | disclosed |
| US-20160318920-A1 | TRPV1 ANTAGONISTS INCLUDING DIHYDROXY SUBSTITUENT AND USES THEREOF | PURDUE PHARMA L.P. | 2016-11-03 | — | — | US | disclosed |
| US-9394293-B2 | TRPV1 antagonists including dihydroxy substituent and uses thereof | PURDUE PHARMA L.P. (US) | 2016-07-19 | — | — | US | disclosed |
| US-9017726-B2 | Biodegradable and thermosensitive poly(organophosphazene)-superparamagnetic nanoparticle complex, preparation method and use thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-04-28 | — | — | US | disclosed |
| EP-2855558-A2 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | Novomer, Inc. (US) | 2015-04-08 | — | — | EP | disclosed |
| US-20140350056-A1 | TRPV1 ANTAGONISTS INCLUDING DIHYDROXY SUBSTITUENT AND USES THEREOF | PURDUE PHARMA L.P. | 2014-11-27 | — | — | US | disclosed |
| US-20140031289-A1 | POLY(ORGANOPHOSPHAZENE) CONTAINING DEGRADATION CONTROLLABLE IONIC GROUP, PREPARATION METHOD THEREOF AND USE THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-01-30 | — | — | US | disclosed |
| WO-2013177546-A2 | POLYCARBONATE POLYOL COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2013-11-28 | — | — | WO | disclosed |
| WO-2013021276-A1 | TRPV1 ANTAGONISTS INCLUDING DIHYDROXY SUBSTITUENT AND USES THEREOF | PURDUE PHARMA L.P. (US) | 2013-02-14 | — | — | WO | disclosed |
| US-20120121517-A1 | BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF | Korean Institute of Science and Technology of Seoul, Republic of Korea | 2012-05-17 | — | — | US | disclosed |
| EP-1472225-A2 | 2-PIPERAZINE-PYRIDINES USEFUL FOR TREATING PAIN | Euro-Celtique S.A. (LU) | 2004-11-03 | — | — | EP | disclosed |
| WO-2004029031-A2 | THERAPEUTIC PIPERAZINE COMPOUNDS | EURO-CELTQUE, S.A. (LU) | 2004-04-08 | — | — | WO | disclosed |
| US-20040044003-A1 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. | 2004-03-04 | — | — | US | disclosed |
| WO-2004011441-A1 | PYRIDAZINYLPIPERAZINE DERIVATIVES FOR TREATING PAIN | EURO-CELTIQUE S.A. (LU) | 2004-02-05 | — | — | WO | disclosed |
| EP-1383505-A2 | INOSINE COMPOUNDS AND THEIR USE FOR TREATING OR PREVENTING AN INFLAMATION OR A REPERFUSION DISEASE | Inotek Pharmaceuticals Corporation (US) | 2004-01-28 | — | — | EP | disclosed |
| US-20040006091-A1 | Therapeutic agents useful for treating or preventing pain | PURDUE PHARMA L.P. | 2004-01-08 | — | — | US | disclosed |
| WO-2003074520-A1 | THIADIAZOLYLPIPERAZINE DERIVATIVES USEFUL FOR TREATING OR PREVENTING PAIN | EURO-CELTIQUE, S.A. (LU) | 2003-09-12 | — | — | WO | disclosed |
| WO-2003066595-A2 | 2 - PIPERAZINE - PYRIDINES USEFUL FOR TREATING PAIN | EURO-CELTIQUE S.A. (LU) | 2003-08-14 | — | — | WO | disclosed |
| US-20030040502-A1 | Inosine compounds and their use for treating or preventing an inflamation or a reperfusion disease | INOTEK PHARMACEUTICALS CORPORATION | 2003-02-27 | — | — | US | disclosed |
| WO-2002076400-A2 | INOSINE COMPOUNDS AND THEIR USE FOR TREATING OR PREVENTING AN INFLAMATION OR A REPERFUSION DISEASE | INOTEK PHARMACEUTICALS CORPORATION (US) | 2002-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120121517-A1 | BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF | PHOSPHO1, HSPA2, FEM1B | KDM4E 2925/4885 |
| US-20040006091-A1 | Therapeutic agents useful for treating or preventing pain | OPRK1, OPRL1, OPRD1 | KDM4E 4612/4885 |
| US-20030040502-A1 | Inosine compounds and their use for treating or preventing an inflamation or a reperfusion disease | NOS2, NOS1, ARG2 | KDM4E 4327/4885 |
| US-20160318920-A1 | TRPV1 ANTAGONISTS INCLUDING DIHYDROXY SUBSTITUENT AND USES THEREOF | TRPV1, TRPV2, TRPA1 | KDM4E 4235/4885 |
| US-20140031289-A1 | POLY(ORGANOPHOSPHAZENE) CONTAINING DEGRADATION CONTROLLABLE IONIC GROUP, PREPARATION METHOD THEREOF AND USE THEREOF | PHOSPHO1, PLCB3, INPP5D | KDM4E 1770/4885 |
| US-20140350056-A1 | TRPV1 ANTAGONISTS INCLUDING DIHYDROXY SUBSTITUENT AND USES THEREOF | TRPV1, TRPV2, TRPA1 | KDM4E 4235/4885 |
| US-20040044003-A1 | Therapeutic agents useful for treating pain | GRIK5, HBS1L, GABRR1 | KDM4E 2915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.