Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11454250 | 0.89 | ALDH2 (0.56) | ALDH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11472640 | 0.86 | ALDH1A1 (0.47) | ALDH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11461479 | 0.86 | ALDH1A1 (0.57) | ALDH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11466087 | 0.85 | ALDH1A1 (0.44) | ALDH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11336522 | 0.79 | ALDH1A1 (0.56) | ALDH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11463460 | 0.78 | ALDH1A1 (0.45) | ALDH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL21103699 | 0.77 | CYP1A2 (0.53) | HPGDMEN1KMT2ACYP2C9MAPT | |
| SCHEMBL21991450 | 0.77 | CYP1A2 (0.53) | HPGDMEN1KMT2ACYP2C9MAPT | |
| SCHEMBL11466088 | 0.77 | MAPT (0.47) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL11452754 | 0.76 | SMN1; SMN2 (0.49) | ALDH1A1KDM4EHPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4199346-A | Herbicides based on 2-dibenzofuranyloxyalkanecarboxylic acid derivatives | AMERICAN HOECHST CORPORATION (US) | 1980-04-22 | — | — | US | disclosed |