Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11461479 | 0.93 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4ERECQLTSHR | |
| SCHEMBL11472640 | 0.82 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4ETSHRHCRTR1 | |
| SCHEMBL11466087 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EHCRTR1MCL1 | |
| SCHEMBL11454250 | 0.80 | ALDH2 (0.56) | ALDH1A1HPGDKDM4ETSHRHCRTR1 | |
| SCHEMBL11109344 | 0.80 | AHR (0.45) | ALDH1A1HPGDKDM4EHCRTR1MCL1 | |
| SCHEMBL11345947 | 0.80 | HCRTR1 (0.46) | ALDH1A1HPGDKDM4EHCRTR1ALDH2 | |
| SCHEMBL11460669 | 0.79 | ALDH2 (0.44) | ALDH1A1HPGDKDM4ETSHRHCRTR1 | |
| SCHEMBL11340277 | 0.79 | HCRTR1 (0.45) | ALDH1A1HPGDKDM4EHCRTR1ALDH2 | |
| SCHEMBL11346947 | 0.78 | ALDH2 (0.43) | ALDH1A1HPGDKDM4ETSHRHCRTR1 | |
| SCHEMBL9834780 | 0.78 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4ERECQLHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035744-A1 | Dibenzo-furane-oxyalkane carboxylic acid esters, process for their preparation, herbicides containing them and their use as herbicides | BASF Aktiengesellschaft (DE) | 1981-09-16 | — | — | EP | disclosed |