Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.55 |
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | SMYD3 | Q9H7B4 | 11/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11461325 | 0.87 | AHR (0.66) | AHRSMYD3EPHX2PGRHDAC3 | |
| SCHEMBL11476171 | 0.84 | AHR (0.48) | AHRAKT1MAOBSMYD3EPHX2 | |
| SCHEMBL3255662 | 0.82 | SMYD3 (0.53) | AHRSMYD3EPHX2 | |
| SCHEMBL3569829 | 0.81 | SMYD3 (0.55) | AHRSMYD3EPHX2HDAC3 | |
| SCHEMBL3581228 | 0.81 | SMYD3 (0.55) | AHRSMYD3EPHX2HDAC3 | |
| SCHEMBL16180358 | 0.79 | PDE3B (0.61) | AHRSMYD3EPHX2HDAC3 | |
| SCHEMBL688890 | 0.78 | TDP2 (0.61) | AHRSMYD3EPHX2HDAC3 | |
| SCHEMBL3574586 | 0.77 | SMYD3 (0.52) | AHRSMYD3EPHX2PGRHDAC3 | |
| SCHEMBL14565018 | 0.77 | SMYD3 (0.50) | AHRSMYD3EPHX2PGRHDAC3 | |
| SCHEMBL7252586 | 0.77 | EPHX2 (0.54) | AHRSMYD3EPHX2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4182774-A | Method of inhibiting blood platelet aggregation with 2-amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts thereof | A. H. ROBINS COMPANY, INCORPORATED (US) | 1980-01-08 | — | — | US | disclosed |
| US-4126635-A | ANTICHOLESTEROL, BLOOD PLATELET AGGREGATION INHIBITION | A. H. ROBINS COMPANY, INCORPORATED (US) | 1978-11-21 | — | — | US | disclosed |
| US-4045576-A | ANTI-INFLAMMATORY METHODS USING 2-AMINO-3-(5- AND 6-)BENZOYLPHENYLACETIC ACIDS, ESTERS AND METAL SALTS THEREOF AND THE COMPOUNDS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-08-30 | — | — | US | disclosed |