Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.84 |
| ▸ | LMNA | P02545 | 1/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE1A | P54750 | 1/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11459769 | 0.92 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAALDH1A1TSHRNPSR1 | |
| SCHEMBL11151054 | 0.90 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNAALDH1A1TSHRNPSR1 | |
| Arprinocid SCHEMBL126655 | 0.81 | ADORA2A (0.60) | SMN1; SMN2LMNAALDH1A1TSHRNPSR1 | |
| Arprinocid SCHEMBL8375355 | 0.81 | ADORA2A (0.60) | SMN1; SMN2LMNAALDH1A1TSHRNPSR1 | |
| Arprinocid SCHEMBL31025603 | 0.81 | ADORA2A (0.60) | SMN1; SMN2LMNAALDH1A1TSHRNPSR1 | |
| SCHEMBL11017499 | 0.81 | PDE4A (0.65) | SMN1; SMN2LMNAMAPK1PDE5APDE4A | |
| Arprinocid SCHEMBL31379008 | 0.81 | ADORA2A (0.60) | SMN1; SMN2LMNAALDH1A1TSHRNPSR1 | |
| SCHEMBL11452542 | 0.81 | HTT (0.59) | SMN1; SMN2LMNAALDH1A1TSHRNPSR1 | |
| SCHEMBL10442061 | 0.81 | CYP1A2 (0.61) | SMN1; SMN2LMNAMAPK1PDE5APDE4A | |
| SCHEMBL11454110 | 0.81 | SMN1; SMN2 (0.79) | SMN1; SMN2LMNAALDH1A1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4189485-A | ANTICOCCIDIAL ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-02-19 | — | — | US | disclosed |