Arprinocid

Arprinocid

SCHEMBL126655

Nc1ncnc2c1ncn2Cc1c(F)cccc1Cl

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA2A P29274 5/20 0.60
▸ PI4KA P42356 4/20 0.60
▸ PI4K2B Q8TCG2 4/20 0.60
▸ PI4K2A Q9BTU6 4/20 0.60
▸ PI4KB Q9UBF8 4/20 0.60
▸ LMNA P02545 1/20 0.55
▸ SMN1; SMN2 Q16637 1/20 0.55
▸ NPSR1 Q6W5P4 2/20 0.54
▸ TSHR P16473 2/20 0.54
▸ ALDH1A1 P00352 1/20 0.54
▸ POLB P06746 1/20 0.54
▸ HPGD P15428 1/20 0.54
▸ PIK3CD O00329 1/20 0.50
▸ HTT P42858 2/20 0.49
▸ MEN1 O00255 1/20 0.49
▸ RECQL P46063 1/20 0.49
▸ KMT2A Q03164 1/20 0.49
▸ ADORA1 P30542 3/20 0.49
▸ NSD2 O96028 2/20 0.47
▸ NSD3 Q9BZ95 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Arprinocid SCHEMBL31379008 1.00 ADORA2A (0.60) ADORA2API4KAPI4K2BPI4K2API4KB
Arprinocid SCHEMBL8375355 1.00 ADORA2A (0.60) ADORA2API4KAPI4K2BPI4K2API4KB
Arprinocid SCHEMBL31025603 1.00 ADORA2A (0.60) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL10962832 0.91 ADORA2A (0.68) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL11016348 0.91 ADORA2A (0.63) ADORA2API4KAPI4K2BPI4K2API4KB
Arprinocid SCHEMBL29801468 0.88 PI4KA (0.45) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL11812620 0.85 ADORA2A (0.60) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL11807952 0.85 ADORA2A (0.60) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL10408838 0.82 PDE4A (0.67) LMNASMN1; SMN2NPSR1TSHRALDH1A1
SCHEMBL11151054 0.82 SMN1; SMN2 (0.67) LMNASMN1; SMN2NPSR1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 325 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11246836-B2 Intramuscular depot of decoquinate compositions and method of prophylaxis and treatment thereof BLUELIGHT PHARMATECH CO., LTD. (CN) 2022-02-15 — — US claimed
US-20210059946-A1 INTRAMUSCULAR DEPOT OF DECOQUINATE COMPOSITIONS AND METHOD OF PROPHYLAXIS AND TREATMENT THEREOF CAS LAMVAC (GUANGZHOU) BIOMEDICAL TECHNOLOGY CO., LTD. (CN) 2021-03-04 — — US claimed
CN-110495523-A A kind of antibiotic-free, veterinary drug preparation of no drug residue and preparation method thereof NANJING HUIMU BIOTECHNOLOGY CO LTD 2019-11-26 — — CN claimed
WO-2019218305-A1 INTRAMUSCULAR DEPOT OF DECOQUINATE COMPOSITIONS AND METHOD OF PROPHYLAXIS AND TREATMENT THEREOF Bluelight Pharmatech Co., Ltd (CN) 2019-11-21 — — WO claimed
CN-109496152-A The method of the intramuscular inventory and its prevention and treatment of deccox composition 广州蓝亮医药科技有限公司 2019-03-19 — — CN claimed
US-20170291886-A1 METHODS FOR TREATING PROTOZOAN INFECTIONS NEOCULI PTY LTD (AU) 2017-10-12 — — US claimed
CN-103099810-B Purine anti-coccidiosis medicine and preparation method thereof GUANGZHOU SCAU EX VETERINARY MEDICINE CO LTD 2015-04-29 — — CN claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 — — US claimed
CN-103061181-B Complex enzyme preparation and technique for preparing dissolving pulp by using same YELLOW RIVER DELTA JINGBO CHEMICAL RESEARCH INSTITUTE CO., LTD. (CN) 2014-10-22 — — CN claimed
CN-103099810-A Purine anti-coccidiosis medicine and preparation method thereof GUANGZHOU SCAU EX VETERINARY MEDICINE CO LTD 2013-05-15 — — CN claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 — — US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 — — US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 — — CN claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 — — US claimed
CN-1196485-C composition for controlling parasitic protozoa BAYER AG (DE) 2005-04-13 — — CN claimed
EP-0828487-B1 AGENTS FOR USE AGAINST PARASITIC PROTOZOA BAYER AG (DE) 2003-11-26 — — EP claimed
US-RE31429-E ANTICOCCIDIAL AGENTS, RANEY NICKEL DESULFURIZATION MERCK & CO., INC. (US) 1983-10-25 — — US claimed
US-4171440-A Process for purification of 9-(2,6-dihalobenzyl)adenines MERCK & CO., INC. (US) 1979-10-16 — — US claimed
US-4100159-A REACTING 2,6-DIHALOBENZYL HALIDES WITH A SALT OF ADENINE IN PRESENCE OF ONIUM SALT PHASE TRANSFER CATALYST MERCK & CO., INC. (US) 1978-07-11 — — US claimed
US-3953597-A POULTRY FEEDS INTERNATIONAL MINERALS & CHEMICAL CORPORATION (US) 1976-04-27 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170291886-A1 METHODS FOR TREATING PROTOZOAN INFECTIONS DPM1, ABCB11, PIGS ADORA2A 2439/4885PI4KA 4533/4885PI4K2B 4771/4885
US-20210059946-A1 INTRAMUSCULAR DEPOT OF DECOQUINATE COMPOSITIONS AND METHOD OF PROPHYLAXIS AND TREATMENT THEREOF HMGCR, DECR1, GYS1 ADORA2A 1520/4885PI4KA 2099/4885PI4K2B 2671/4885
US-11246836-B2 Intramuscular depot of decoquinate compositions and method of prophylaxis and treatment thereof HMGCR, DECR1, GYS1 ADORA2A 1520/4885PI4KA 2099/4885PI4K2B 2671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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