Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.60 |
| ▸ | PI4KA | P42356 | 4/20 | 0.60 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.60 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.60 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.49 |
| ▸ | NSD2 | O96028 | 2/20 | 0.47 |
| ▸ | NSD3 | Q9BZ95 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arprinocid SCHEMBL126655 | 1.00 | ADORA2A (0.60) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| Arprinocid SCHEMBL31379008 | 1.00 | ADORA2A (0.60) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| Arprinocid SCHEMBL31025603 | 1.00 | ADORA2A (0.60) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL10962832 | 0.91 | ADORA2A (0.68) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11016348 | 0.91 | ADORA2A (0.63) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| Arprinocid SCHEMBL29801468 | 0.88 | PI4KA (0.45) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11812620 | 0.85 | ADORA2A (0.60) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11807952 | 0.85 | ADORA2A (0.60) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL10408838 | 0.82 | PDE4A (0.67) | LMNASMN1; SMN2NPSR1TSHRALDH1A1 | |
| SCHEMBL11151054 | 0.82 | SMN1; SMN2 (0.67) | LMNASMN1; SMN2NPSR1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0896535-A1 | USE OF SUBSTITUTED ARYL IMIDAZOLES | BAYER AG (DE) | 1999-02-17 | — | — | EP | disclosed |
| WO-1997036582-A1 | USE OF SUBSTITUTED ARYL IMIDAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-09 | — | — | WO | disclosed |