Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 4/20 | 0.46 |
| ▸ | TYK2 | P29597 | 2/20 | 0.42 |
| ▸ | KMO | O15229 | 5/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11471405 | 0.98 | CNR1 (0.47) | IP6K1CNR1TYK2KMOOPRK1 | |
| SCHEMBL11453944 | 0.87 | IP6K1 (0.43) | IP6K1CNR1TYK2 | |
| SCHEMBL11472242 | 0.80 | RHEB (0.46) | CNR1SCN9ACNR2 | |
| SCHEMBL14089846 | 0.78 | IP6K1 (0.49) | IP6K1CNR1KMOSCN9ACNR2 | |
| SCHEMBL14612145 | 0.77 | ACACB (0.42) | IP6K1TYK2OPRK1 | |
| SCHEMBL30843203 | 0.77 | ALDH1A1 (0.43) | IP6K1CNR1TYK2 | |
| SCHEMBL4946467 | 0.77 | IP6K1 (0.48) | IP6K1CNR1KMOSCN9ACNR2 | |
| SCHEMBL9653496 | 0.76 | KDM4E (0.45) | — | |
| SCHEMBL30990017 | 0.76 | KDM4E (0.45) | — | |
| SCHEMBL369068 | 0.74 | CNR1 (0.40) | IP6K1CNR1TYK2SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4181658-A | Certain nicotinamido-n-benzoic acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-01 | — | — | US | disclosed |
| US-4157395-A | TREATMENT OF DIABETES | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-06-05 | — | — | US | disclosed |