Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 20/20 | 0.68 |
| ▸ | OPRM1 | P35372 | 19/20 | 0.68 |
| ▸ | OPRD1 | P41143 | 19/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 19/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11471401 | 0.95 | OPRL1 (0.67) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL11459988 | 0.90 | OPRL1 (0.82) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL11461889 | 0.81 | OPRL1 (1.00) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL9063100 | 0.81 | OPRM1 (0.54) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL11467822 | 0.80 | OPRM1 (0.46) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL3538856 | 0.78 | CHRNB4 (0.55) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL31568823 | 0.78 | CHRNB4 (0.55) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL3538855 | 0.78 | CHRNB4 (0.55) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL5187982 | 0.78 | CHRNB4 (0.55) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL13403254 | 0.78 | CHRNB4 (0.55) | OPRL1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4196124-A | ANTIOBESITY AGENTS | SCHERING CORPORATION (US) | 1980-04-01 | — | — | US | disclosed |
| US-4173566-A | CHEMICAL INTERMEDIATE FOR AN ANTIOBESITY AGENT | SCHERING CORPORATION (US) | 1979-11-06 | — | — | US | disclosed |
| US-4140780-A | ANTIOBESITY AGENTS | SCHERING CORPORATION (US) | 1979-02-20 | — | — | US | disclosed |
| US-4052383-A | ANTIOBESITY | SCHERING CORPORATION (US) | 1977-10-04 | — | — | US | disclosed |