SCHEMBL9063100

SCHEMBL9063100

CC(N)C1CCCCN1C(c1ccccc1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 14/20 0.54
OPRD1 P41143 14/20 0.54
OPRK1 P41145 14/20 0.54
OPRL1 P41146 14/20 0.54
KDM4E B2RXH2 1/20 0.43
L3MBTL3 Q96JM7 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11471401 0.86 OPRL1 (0.67) OPRM1OPRD1OPRK1OPRL1L3MBTL3
SCHEMBL11463527 0.81 OPRL1 (0.68) OPRM1OPRD1OPRK1OPRL1
SCHEMBL11465332 0.79 OPRM1 (0.44) OPRM1OPRD1OPRK1OPRL1KDM4E
SCHEMBL11467822 0.74 OPRM1 (0.46) OPRM1OPRD1OPRK1OPRL1KDM4E
SCHEMBL11459988 0.73 OPRL1 (0.82) OPRM1OPRD1OPRK1OPRL1
SCHEMBL28853355 0.72 OPRM1 (0.46) OPRM1OPRD1OPRK1OPRL1KDM4E
SCHEMBL21850215 0.72 OPRM1 (0.46) OPRM1OPRD1OPRK1OPRL1KDM4E
SCHEMBL13291353 0.71 KDM4E (0.56) OPRM1OPRD1OPRK1OPRL1KDM4E
SCHEMBL14257980 0.71 KDM4E (0.56) OPRM1OPRD1OPRK1OPRL1KDM4E
SCHEMBL24359263 0.71 OPRM1 (0.42) OPRM1OPRD1OPRK1OPRL1L3MBTL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8333361-A None JP disclosed
JP-8333360-A None JP disclosed
JP-H08333361-A PRODUCTION OF 2-NAPHTHAMIDE DERIVATIVE FUJIREBIO INC 1996-12-17 JP disclosed
JP-H08333360-A PRODUCTION OF NAPHTHAMIDE DERIVATIVE FUJIREBIO INC 1996-12-17 JP disclosed