Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11463389 | 0.90 | KMT2A (0.71) | KMT2ANPC1RAB9AMEN1MAPK8 | |
| SCHEMBL2837047 | 0.87 | KMT2A (0.53) | KMT2ANPC1RAB9AMEN1MAPK8 | |
| SCHEMBL11411479 | 0.86 | MAPT (0.58) | KMT2ANPC1RAB9AMEN1MAPK8 | |
| SCHEMBL11467626 | 0.85 | KMT2A (0.61) | KMT2ANPC1RAB9AMEN1MAPK8 | |
| SCHEMBL11461259 | 0.84 | MAPK8 (0.56) | KMT2ANPC1RAB9AMEN1MAPK8 | |
| SCHEMBL11480484 | 0.83 | MAPK8 (0.65) | KMT2ARAB9AMEN1MAPK8TP53 | |
| SCHEMBL11462148 | 0.83 | KMT2A (0.56) | KMT2ANPC1RAB9AMEN1MAPK8 | |
| SCHEMBL11463568 | 0.81 | MAPT (0.58) | KMT2ANPC1RAB9AMEN1MAPK8 | |
| SCHEMBL11471226 | 0.81 | KDM4E (0.58) | KMT2ANPC1RAB9AMEN1MAPK8 | |
| SCHEMBL11465002 | 0.81 | TNKS (0.58) | KMT2AMEN1MAPK8POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4197403-A | ANTIINFLAMMATORY, IMMUNOSUPPRESSIVE, FUNGICIDE | WESTWOOD PHARMACEUTICALS INC. (US) | 1980-04-08 | — | — | US | claimed |