SCHEMBL11465002

SCHEMBL11465002

Fc1ccc(Nc2nc3ccccc3n3ccnc23)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 1/20 0.58
MAPK8 P45983 7/20 0.56
SMN1; SMN2 Q16637 2/20 0.51
HPGD P15428 2/20 0.51
LMNA P02545 1/20 0.51
MAPK1 P28482 1/20 0.51
HSD17B10 Q99714 1/20 0.51
MAPT P10636 4/20 0.50
GAA P10253 1/20 0.50
HCRTR1 O43613 1/20 0.50
KDM4E B2RXH2 3/20 0.47
ALDH1A1 P00352 1/20 0.47
MEN1 O00255 1/20 0.46
POLB P06746 1/20 0.46
KMT2A Q03164 1/20 0.46
PPARG P37231 1/20 0.46
NR2E3 Q9Y5X4 1/20 0.46
NCOR2 Q9Y618 1/20 0.46
LCK P06239 2/20 0.45
ATM Q13315 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11480484 0.89 MAPK8 (0.65) TNKSMAPK8SMN1; SMN2HPGDLMNA
SCHEMBL11471226 0.87 KDM4E (0.58) TNKSMAPK8SMN1; SMN2HPGDLMNA
SCHEMBL11461259 0.87 MAPK8 (0.56) TNKSMAPK8SMN1; SMN2HPGDLMNA
SCHEMBL11463568 0.87 MAPT (0.58) TNKSMAPK8SMN1; SMN2HPGDLMNA
SCHEMBL11411479 0.87 MAPT (0.58) TNKSMAPK8SMN1; SMN2HPGDLMNA
SCHEMBL11460081 0.84 MAPK8 (0.59) MAPK8SMN1; SMN2HPGDLMNAMAPK1
SCHEMBL11461246 0.83 KMT2A (0.53) TNKSMAPK8HPGDHCRTR1KDM4E
SCHEMBL11460178 0.83 LCK (0.61) MAPK8SMN1; SMN2HPGDLMNAMAPK1
SCHEMBL11463004 0.83 MAPK8 (0.52) MAPK8SMN1; SMN2HPGDHSD17B10MAPT
SCHEMBL11463548 0.81 KMT2A (0.69) MAPK8SMN1; SMN2HPGDLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4197403-A ANTIINFLAMMATORY, IMMUNOSUPPRESSIVE, FUNGICIDE WESTWOOD PHARMACEUTICALS INC. (US) 1980-04-08 US claimed