Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11357568 | 0.86 | KMT2A (0.50) | KMT2AMAPTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL11751874 | 0.85 | HPGD (0.51) | KMT2AMAPTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL11008237 | 0.81 | CYP2C9 (0.62) | KMT2AMAPTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL6059927 | 0.81 | ALDH1A1 (0.51) | KMT2AMAPTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL11386183 | 0.81 | MAPT (0.46) | MAPTHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL11454583 | 0.80 | KMT2A (0.44) | KMT2AMAPTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL5076584 | 0.76 | SMN1; SMN2 (0.65) | KMT2AMAPTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL11754394 | 0.75 | ALDH1A1 (0.56) | KMT2AMAPTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL4595089 | 0.75 | MAPT (0.64) | KMT2AMAPTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL10662162 | 0.75 | MAPK14 (0.49) | MAPTHSD17B10ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4207319-A | CORONARY VASODILATOR | ALBERT ROLLAND S.A. (FR) | 1980-06-10 | — | — | US | disclosed |
| US-4029808-A | Thienyl phenyl O-(aminoalkyl)-ketone oxime and furyl phenyl O-(aminoalkyl)-ketone oxime coronary vasodilators | C.E.R.P.H.A. A FRENCH SOCIETY ORGANISED UNDER THE LAWS OF FRANCE (FR) | 1977-06-14 | — | — | US | disclosed |