Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091405 | 0.81 | RAB9A (0.65) | ALDH1A1KMT2ARAB9AMAPTHPGD | |
| SCHEMBL15207580 | 0.80 | KMT2A (0.58) | ALDH1A1KMT2ARAB9AMAPTMEN1 | |
| SCHEMBL13142806 | 0.79 | KMT2A (0.62) | ALDH1A1KMT2ARAB9AMAPTMEN1 | |
| SCHEMBL8305811 | 0.78 | GFER (0.61) | ALDH1A1KMT2ARAB9AMAPTMEN1 | |
| SCHEMBL27983727 | 0.76 | HTT (0.69) | ALDH1A1KMT2ARAB9AMAPTMEN1 | |
| SCHEMBL11463561 | 0.75 | KMT2A (0.52) | ALDH1A1KMT2ARAB9AMAPTMEN1 | |
| SCHEMBL9726804 | 0.75 | MAPT (0.82) | ALDH1A1KMT2ARAB9AMAPTMEN1 | |
| SCHEMBL11576124 | 0.74 | MAPK13 (0.58) | ALDH1A1KMT2ARAB9AMAPTHPGD | |
| SCHEMBL8306297 | 0.73 | MAPT (0.57) | ALDH1A1KMT2ARAB9AMAPTMEN1 | |
| SCHEMBL295414 | 0.73 | SMN1; SMN2 (0.57) | ALDH1A1KMT2ARAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4029808-A | Thienyl phenyl O-(aminoalkyl)-ketone oxime and furyl phenyl O-(aminoalkyl)-ketone oxime coronary vasodilators | C.E.R.P.H.A. A FRENCH SOCIETY ORGANISED UNDER THE LAWS OF FRANCE (FR) | 1977-06-14 | — | — | US | disclosed |