SCHEMBL1146478

SCHEMBL1146478

CCOC(CCCO)OCC

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
THRB P10828 1/20 0.36
LMNA P02545 3/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 1/20 0.33
EPHX1 P07099 1/20 0.33
PTPN1 P18031 1/20 0.31
SMPD1 P17405 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5705793 0.92 SMN1; SMN2 (0.39) ALDH1A1THRBLMNASMN1; SMN2HSD17B10
SCHEMBL27496194 0.88 THRB (0.32) ALDH1A1THRBLMNASMN1; SMN2
SCHEMBL440376 0.83 THRB (0.40) ALDH1A1THRBLMNA
SCHEMBL7753817 0.83 THRB (0.44) THRBLMNAEPHX1SMPD1
SCHEMBL6227646 0.83 THRB (0.44) THRBLMNAEPHX1SMPD1
SCHEMBL12348921 0.83 SMN1; SMN2 (0.32) ALDH1A1LMNASMN1; SMN2HSD17B10MEN1
SCHEMBL12349185 0.83 SMN1; SMN2 (0.32) ALDH1A1LMNASMN1; SMN2HSD17B10MEN1
Ammonia Solution, Strong SCHEMBL7956004 0.81 THRB (0.38) ALDH1A1THRBLMNA
SCHEMBL16318547 0.81
SCHEMBL8431364 0.80 THRB (0.42) THRBLMNAEPHX1SMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024146541-A1 MACROCYCLIC COMPOUNDS AS USP1 INHIBITORS GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) 2024-07-11 WO disclosed
US-8076412-B2 Water-soluble polymer alkanals NEKTAR THERAPEUTICS (US) 2011-12-13 US disclosed
US-20110034737-A1 Water-Soluble Polymer Alkanals NEKTAR THERAPEUTICS (US) 2011-02-10 US disclosed
CN-1842568-A Polymer alloy, crosslinked object, and fuel hose ZEON CORP (JP) 2006-10-04 CN disclosed
CN-1688653-A Polymer alloy, crosslinked material, and fuel pipe ZEON CORP (JP) 2005-10-26 CN disclosed
EP-0822217-B1 HETEROTELECHELIC BLOCK COPOLYMERS AND PROCESS FOR PRODUCING THE SAME KATAOKA KAZUNORI (JP) 2002-10-23 EP disclosed
CN-1067073-C Acyclic nucleoside derivatives MEDIVIR AB (CH) 2001-06-13 CN disclosed
US-5925720-A CARRIER FOR DRUG DELIVERY Kataoka, Kazunori (JP) 1999-07-20 US disclosed
CN-1210537-A Acyclic nucleoside derivatives MEDIVIR AB (CH) 1999-03-10 CN disclosed
EP-0822217-A1 HETEROTELECHELIC BLOCK COPOLYMERS AND PROCESS FOR PRODUCING THE SAME Kataoka, Kazunori (JP) 1998-02-04 EP disclosed
US-4847229-A Process for hydroformylation of unsaturated compounds using iron carbonyl catalysts THE DOW CHEMICAL COMPANY (US) 1989-07-11 US disclosed
US-4782188-A Process for hydroformylation of unsaturated compounds using iron carbonyl catalysts THE DOW CHEMICAL COMPANY (US) 1988-11-01 US disclosed
US-4374999-A RHODIUM-COBALT CLUSTER CATALYST LOADED ON AMINE RESIN THE DOW CHEMICAL COMPANY (US) 1983-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110034737-A1 Water-Soluble Polymer Alkanals ALK, ALKBH3, AQP1 ALDH1A1 77/4885THRB 4877/4885LMNA 2044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.