Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.35 |
| ▸ | USP19 | O94966 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3078624 | 0.77 | BUB1 (0.37) | SMN1; SMN2HSD11B1 | |
| Hydrochloric Acid SCHEMBL21225114 | 0.76 | GRM5 (0.33) | SMN1; SMN2USP19GRM5HSD11B1ALDH1A1 | |
| SCHEMBL21246355 | 0.76 | USP19 (0.36) | SMN1; SMN2USP19GRM5 | |
| SCHEMBL3733841 | 0.75 | KDM1A (0.38) | SMN1; SMN2 | |
| SCHEMBL13803813 | 0.74 | USP19 (0.41) | SMN1; SMN2USP19GRM5 | |
| SCHEMBL21246350 | 0.73 | USP19 (0.34) | SMN1; SMN2USP19GRM5 | |
| SCHEMBL21225110 | 0.73 | GRM5 (0.32) | SMN1; SMN2GRM5 | |
| SCHEMBL25275893 | 0.72 | ITGB3 (0.30) | — | |
| SCHEMBL5336354 | 0.72 | SMN1; SMN2 (0.36) | SMN1; SMN2USP19GRM5 | |
| SCHEMBL12243268 | 0.72 | CYP11B1 (0.44) | SMN1; SMN2USP19GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228179-A | ANTICONVULSANTS | WARNER-LAMBERT COMPANY (US) | 1980-10-14 | — | — | US | disclosed |