Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.60 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10563341 | 1.00 | ADRB2 (0.60) | ADRB2ADRB3ADRB1KDM4EALDH1A1 | |
| SCHEMBL10563338 | 1.00 | ADRB2 (0.60) | ADRB2ADRB3ADRB1KDM4EALDH1A1 | |
| SCHEMBL11465016 | 1.00 | ADRB2 (0.60) | ADRB2ADRB3ADRB1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL10565533 | 0.99 | ADRB2 (0.59) | ADRB2ADRB3ADRB1KDM4EALDH1A1 | |
| SCHEMBL11359611 | 0.90 | ADRB3 (0.58) | ADRB2ADRB3ADRB1KDM4EALDH1A1 | |
| SCHEMBL11359598 | 0.90 | ADRB3 (0.58) | ADRB2ADRB3ADRB1KDM4EALDH1A1 | |
| SCHEMBL10657631 | 0.90 | ADRB1 (0.73) | ADRB2ADRB3ADRB1KDM4EALDH1A1 | |
| SCHEMBL10563514 | 0.89 | ADRB2 (0.56) | ADRB2ADRB3ADRB1KDM4EALDH1A1 | |
| SCHEMBL10563518 | 0.89 | ADRB2 (0.56) | ADRB2ADRB3ADRB1KDM4EALDH1A1 | |
| SCHEMBL11480459 | 0.89 | ADRB2 (0.78) | ADRB2ADRB3ADRB1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007205-A1 | Optically active phenethanolamines, their formulations, use and preparation | ELI LILLY AND COMPANY (US) | 1980-01-23 | — | — | EP | disclosed |