Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIMP3 | P35625 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.47 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | CBX7 | O95931 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11468629 | 0.97 | TIMP3 (0.53) | TIMP3MEN1KMT2ATDP1USP2 | |
| SCHEMBL11407252 | 0.97 | TIMP3 (0.53) | TIMP3MEN1KMT2ATDP1USP2 | |
| SCHEMBL11416499 | 0.89 | KMT2A (0.49) | TIMP3MEN1KMT2ATDP1USP2 | |
| SCHEMBL11413358 | 0.87 | TIMP3 (0.52) | TIMP3MEN1KMT2ATDP1USP2 | |
| SCHEMBL11426644 | 0.86 | TIMP3 (0.51) | TIMP3MEN1KMT2ATDP1USP2 | |
| SCHEMBL11511524 | 0.84 | TIMP3 (0.53) | TIMP3MEN1KMT2ATDP1USP2 | |
| SCHEMBL11512365 | 0.83 | KCNMA1 (0.46) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL11466127 | 0.83 | TIMP3 (0.52) | TIMP3MEN1KMT2ATDP1USP2 | |
| SCHEMBL11415406 | 0.82 | TIMP3 (0.45) | TIMP3MEN1KMT2ATDP1USP2 | |
| SCHEMBL11515015 | 0.81 | KCNMA1 (0.48) | TIMP3MEN1KMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008154-A1 | Ureylene phenylene anionic naphthalene-sulfonic acids, their use as complement system inhibitors in a body fluid and process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-02-20 | — | — | EP | disclosed |
| US-4180587-A | Ureylene phenylene anionic naphthalenesulfonic acids as complement inhibitors | AMERICAN CYANAMID COMPANY (US) | 1979-12-25 | — | — | US | disclosed |