Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 13/20 | 0.61 |
| ▸ | PIM2 | Q9P1W9 | 8/20 | 0.61 |
| ▸ | FLT3 | P36888 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.50 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29448008 | 0.88 | PIM1 (0.71) | PIM1PIM2LMNATP53CSNK2A1 | |
| SCHEMBL5393443 | 0.88 | PIM1 (0.71) | PIM1PIM2LMNATP53CSNK2A1 | |
| SCHEMBL22777752 | 0.88 | PIM1 (0.71) | PIM1PIM2LMNATP53CSNK2A1 | |
| SCHEMBL11456119 | 0.87 | PIM1 (0.61) | PIM1PIM2FLT3LMNATP53 | |
| SCHEMBL3487776 | 0.86 | FLT3 (0.76) | PIM1PIM2FLT3LMNATP53 | |
| SCHEMBL3499199 | 0.85 | PIM1 (0.59) | PIM1PIM2LMNATP53CSNK2A1 | |
| SCHEMBL23512542 | 0.83 | LMNA (0.58) | PIM1PIM2LMNATP53CSNK2A1 | |
| SCHEMBL11463231 | 0.83 | PIM1 (0.58) | PIM1PIM2LMNATP53CSNK2A1 | |
| SCHEMBL11464783 | 0.81 | PTPN22 (0.57) | PIM1PIM2LMNATP53PTPN22 | |
| SCHEMBL7567706 | 0.79 | FLT3 (0.65) | PIM1FLT3TP53CSNK2A1CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4213999-A | Inhibition of lipogenesis | SHELL OIL COMPANY (US) | 1980-07-22 | — | — | US | disclosed |