Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.76 |
| ▸ | PIM1 | P11309 | 9/20 | 0.66 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.56 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31060249 | 0.86 | FLT3 (1.00) | FLT3PIM1PIM2LMNACA2 | |
| SCHEMBL11465166 | 0.86 | PIM1 (0.61) | FLT3PIM1PIM2LMNATP53 | |
| SCHEMBL6021894 | 0.85 | FLT3 (0.76) | FLT3PIM1PIM2LMNATP53 | |
| SCHEMBL3488095 | 0.83 | FLT3 (0.73) | FLT3PIM1PIM2LMNATP53 | |
| SCHEMBL27448783 | 0.83 | FLT3 (0.54) | FLT3PIM1PIM2LMNATP53 | |
| SCHEMBL7567706 | 0.81 | FLT3 (0.65) | FLT3PIM1TP53CSNK2A1CSNK2A2 | |
| SCHEMBL14994660 | 0.81 | FLT3 (0.75) | FLT3NPC1TSHRHPGDMAPT | |
| SCHEMBL7410565 | 0.81 | PIM1 (0.66) | FLT3PIM1PIM2LMNATP53 | |
| SCHEMBL648526 | 0.81 | FLT3 (0.76) | FLT3PIM1PIM2LMNATP53 | |
| SCHEMBL25256269 | 0.79 | PIM1 (0.64) | FLT3PIM1PIM2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109438403-A | A kind of preparation method of 5- aminobenzofur -2- Ethyl formate | 凯瑞斯德生化(苏州)有限公司 | 2019-03-08 | — | — | CN | claimed |
| CN-112543764-B | Amide compound with BET proteolytic induction effect and medical application thereof | 田边三菱制药株式会社 | 2024-05-10 | — | — | CN | disclosed |
| US-11542273-B2 | Amide compound having bet proteolysis-inducing action and medicinal application thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2023-01-03 | — | — | US | disclosed |
| US-20210284654-A1 | AMIDE COMPOUND HAVING BET PROTEOLYSIS-INDUCING ACTION AND MEDICINAL APPLICATION THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2021-09-16 | — | — | US | disclosed |
| EP-3819305-A1 | AMIDE COMPOUND HAVING BET PROTEOLYSIS-INDUCING ACTION AND MEDICINAL APPLICATION THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2021-05-12 | — | — | EP | disclosed |
| CN-112543764-A | Amide compound with BET proteolysis induction effect and medical application thereof | 田边三菱制药株式会社 | 2021-03-23 | — | — | CN | disclosed |
| US-10752624-B2 | Kinase inhibitors | ORIGENIS GMBH (DE) | 2020-08-25 | — | — | US | disclosed |
| WO-2020009176-A1 | AMIDE COMPOUND HAVING BET PROTEOLYSIS-INDUCING ACTION AND MEDICINAL APPLICATION THEREOF | 田辺三菱製薬株式会社 | 2020-01-09 | — | — | WO | disclosed |
| CN-109626550-A | The application of 5,6- dihydro -4- hydroxyl -6- methylthiophene [2,3-b] sulphur pyrans -7,7- dioxide | 凯瑞斯德生化(苏州)有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-109626550-A | The application of 5,6- dihydro -4- hydroxyl -6- methylthiophene [2,3-b] sulphur pyrans -7,7- dioxide | 凯瑞斯德生化(苏州)有限公司 | 2019-04-16 | — | — | CN | disclosed |
| EP-1064281-B1 | BENZOHETEROCYCLIC DISTAMYCIN DERIVATIVES, PROCESS FOR PREPARING THEM, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA ITALIA SPA (IT) | 2005-05-25 | — | — | EP | disclosed |
| EP-0937070-B1 | BENZOHETEROCYCLIC DISTAMYCIN DERIVATIVES, PROCESS FOR PREPARING THEM, AND THEIR USE AS ANTITUMOR AND ANTIVIRAL AGENTS | PHARMACIA ITALIA SPA (IT) | 2003-12-03 | — | — | EP | disclosed |
| EP-0738722-B1 | 5-Amino-benzofuran-2-carboxylic acid derivatives | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6458768-B1 | ANTITUMOR AGENTS THAT CAN BE FORMULATED WITH A COMPOUND ALTERNATIVELY, CAN BE ADMINISTERED IN A MIXTURE OF DRUGS | PHARMACIA & UPJOHN, S.P.A. (IT) | 2002-10-01 | — | — | US | disclosed |
| EP-1064281-A1 | BENZOHETEROCYCLIC DISTAMYCIN DERIVATIVES, PROCESS FOR PREPARING THEM, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 2001-01-03 | — | — | EP | disclosed |
| US-6153642-A | Benzoheterocyclic distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents | PHARMACIA & UPJOHN S.P.A. (IT) | 2000-11-28 | — | — | US | disclosed |
| WO-1999050266-A1 | BENZOHETEROCYCLIC DISTAMYCIN DERIVATIVES, PROCESS FOR PREPARING THEM, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-10-07 | — | — | WO | disclosed |
| EP-0937070-A1 | BENZOHETEROCYCLIC DISTAMYCIN DERIVATIVES, PROCESS FOR PREPARING THEM, AND THEIR USE AS ANTITUMOR AND ANTIVIRAL AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998021202-A1 | BENZOHETEROCYCLIC DISTAMYCIN DERIVATIVES, PROCESS FOR PREPARING THEM, AND THEIR USE AS ANTITUMOR AND ANTIVIRAL AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-05-22 | — | — | WO | disclosed |
| EP-0738722-A1 | 5-Amino-benzofuran-2-carboxylic acid derivatives | MERCK PATENT GmbH (DE) | 1996-10-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11542273-B2 | Amide compound having bet proteolysis-inducing action and medicinal application thereof | BET1, BRD4, PHKB | FLT3 2895/4885PIM1 1555/4885PIM2 2022/4885 |
| US-20210284654-A1 | AMIDE COMPOUND HAVING BET PROTEOLYSIS-INDUCING ACTION AND MEDICINAL APPLICATION THEREOF | BET1, BRD4, PHKB | FLT3 2905/4885PIM1 1558/4885PIM2 1970/4885 |
| US-10752624-B2 | Kinase inhibitors | LRRK2, MYLK2, MYLK | FLT3 407/4885PIM1 489/4885PIM2 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.