Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 3/20 | 0.35 |
| ▸ | FLT4 | P35916 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11331873 | 0.85 | KDM4E (0.44) | KDM4ELMNAFLT1FLT4KDR | |
| SCHEMBL11465649 | 0.83 | FLT1 (0.37) | FLT1FLT4KDRMAPTALDH1A1 | |
| SCHEMBL11466622 | 0.81 | CNR2 (0.32) | FLT1FLT4KDRPTGS1CNR2 | |
| SCHEMBL11481376 | 0.78 | CCR2 (0.33) | — | |
| SCHEMBL11218394 | 0.77 | KDM4E (0.43) | KDM4ELMNAFLT1FLT4KDR | |
| SCHEMBL11466898 | 0.76 | EGFR (0.38) | LMNAMAPTPTGS1ALDH1A1PTGS2 | |
| SCHEMBL11332869 | 0.72 | ESR1 (0.41) | KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL11345629 | 0.72 | NR1I2 (0.36) | KDM4EMAPTALDH1A1HSD11B1POLB | |
| SCHEMBL22503116 | 0.70 | FLT1 (0.59) | KDM4ELMNAFLT1FLT4KDR | |
| SCHEMBL11336181 | 0.70 | KMT2A (0.41) | LMNATP53ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010844-A1 | Novel N,N'-bis(trifluoromethylsulfonyl)oxamides, chemiluminescent compositions containing them and processes for generating chemiluminescence employing said compositions | AMERICAN CYANAMID COMPANY (US) | 1980-05-14 | — | — | EP | claimed |