Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11331873 | 0.87 | KDM4E (0.44) | KDM4ELMNATP53MAPTCA12 | |
| SCHEMBL2033767 | 0.85 | KMT2A (0.41) | LMNATP53CA1CA2CA9 | |
| SCHEMBL10141931 | 0.77 | ALDH1A1 (0.41) | KDM4ELMNACA12CA1CA2 | |
| SCHEMBL11465731 | 0.77 | KDM4E (0.37) | KDM4ELMNATP53MAPTALDH1A1 | |
| SCHEMBL10665928 | 0.76 | LMNA (0.64) | KDM4ELMNATP53MAPTCA12 | |
| SCHEMBL11336181 | 0.74 | KMT2A (0.41) | LMNATP53CA1CA2CA9 | |
| SCHEMBL11336357 | 0.74 | TSHR (0.41) | TP53CA12CA1CA2CA9 | |
| SCHEMBL9178616 | 0.74 | KMT2A (0.62) | KDM4ELMNATP53MAPTALDH1A1 | |
| SCHEMBL11345629 | 0.73 | NR1I2 (0.36) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL11332869 | 0.73 | ESR1 (0.41) | KDM4ELMNAMAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333759-A | Herbicidal 5-cyano-2,3-dihydro-benzofuran-2-ones | FISONS LIMITED (GB) | 1982-06-08 | — | — | US | disclosed |
| US-4263037-A | 5-Cyano-2,3-dihydrobenzofurans useful as herbicides | FISONS LIMITED (GB) | 1981-04-21 | — | — | US | disclosed |
| US-4222767-A | Certain herbicidal sulfonates and sulfamates | FISONS LIMITED (GB) | 1980-09-16 | — | — | US | disclosed |
| EP-0007719-A2 | Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives | FBC LIMITED (GB) | 1980-02-06 | — | — | EP | disclosed |
| US-4183741-A | POSTEMERGENCE | FISONS LIMITED (GB) | 1980-01-15 | — | — | US | disclosed |
| US-4163846-A | HERBICIDES | FISONS LIMITED (GB) | 1979-08-07 | — | — | US | disclosed |
| US-4162154-A | BENZOFURAN DERIVATIVES | FISONS LIMITED (GB) | 1979-07-24 | — | — | US | disclosed |