Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | HPN | P05981 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29218271 | 0.85 | KEAP1 (0.50) | KEAP1NFE2L2HPNALDH1A1LMNA | |
| SCHEMBL30923148 | 0.82 | HTT (0.68) | KEAP1NFE2L2HPNALDH1A1RAB9A | |
| SCHEMBL20501067 | 0.82 | HTT (0.68) | KEAP1NFE2L2HPNALDH1A1RAB9A | |
| SCHEMBL9769314 | 0.81 | HTT (0.66) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL16062208 | 0.78 | TP53 (0.49) | KEAP1NFE2L2HPNALDH1A1RAB9A | |
| SCHEMBL28287787 | 0.78 | HPN (0.49) | KEAP1NFE2L2HPNALDH1A1LMNA | |
| SCHEMBL19657952 | 0.78 | KEAP1 (0.56) | KEAP1NFE2L2ALDH1A1RAB9ANPC1 | |
| SCHEMBL5958372 | 0.76 | NOTUM (0.53) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL3929733 | 0.75 | GRM5 (0.58) | KEAP1NFE2L2HPNALDH1A1RAB9A | |
| SCHEMBL2643542 | 0.75 | KEAP1 (0.52) | KEAP1NFE2L2HPNALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0011295-A1 | Yellow monoazo dyes of the 2-hydroxydibenzofuran series; their preparation and use for dyeing and printing synthetic hydrophobic fibres | Montedison S.p.A. (IT) | 1980-05-28 | — | — | EP | disclosed |