Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 8/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.33 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24795887 | 0.68 | DRD2 (0.47) | SIGMAR1ALDH1A1MEN1KMT2ADRD2 | |
| SCHEMBL19418157 | 0.67 | TDP1 (0.46) | ALDH1A1MEN1TSHRKMT2AKDM4E | |
| SCHEMBL15061509 | 0.66 | TDP1 (0.44) | ALDH1A1MEN1TSHRKMT2AKDM4E | |
| SCHEMBL11466284 | 0.66 | MAOA (0.34) | SIGMAR1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6604174 | 0.65 | TDP1 (0.41) | SIGMAR1ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL318106 | 0.65 | MEN1 (0.58) | SIGMAR1ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL26228226 | 0.64 | TDP1 (0.40) | SIGMAR1ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL26259998 | 0.64 | TDP1 (0.42) | ALDH1A1MEN1TSHRKMT2ATDP1 | |
| SCHEMBL30118783 | 0.63 | TDP1 (0.39) | SIGMAR1ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL17717584 | 0.63 | TDP1 (0.39) | SIGMAR1ALDH1A1MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4181661-A | SCHIZOPHRENIA, PSYCHOLOGICAL DISORDERS | MERCK & CO., INC. (US) | 1980-01-01 | — | — | US | disclosed |