Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11458352 | 1.00 | OPRL1 (0.46) | OPRL1OPRM1OPRK1OPRD1HSD11B1 | |
| SCHEMBL11458351 | 1.00 | OPRL1 (0.46) | OPRL1OPRM1OPRK1OPRD1HSD11B1 | |
| SCHEMBL11457604 | 0.91 | OPRL1 (0.44) | OPRL1OPRM1OPRK1OPRD1HSD11B1 | |
| SCHEMBL11469103 | 0.91 | OPRL1 (0.44) | OPRL1OPRM1OPRK1OPRD1HSD11B1 | |
| SCHEMBL11457605 | 0.91 | OPRL1 (0.44) | OPRL1OPRM1OPRK1OPRD1HSD11B1 | |
| SCHEMBL11457551 | 0.89 | OPRL1 (0.49) | OPRL1OPRM1OPRK1OPRD1CYP2C9 | |
| SCHEMBL11475337 | 0.89 | OPRL1 (0.49) | OPRL1OPRM1OPRK1OPRD1CYP2C9 | |
| SCHEMBL11457550 | 0.89 | OPRL1 (0.49) | OPRL1OPRM1OPRK1OPRD1CYP2C9 | |
| SCHEMBL10571723 | 0.88 | OPRL1 (0.46) | OPRL1OPRM1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL2892148 | 0.85 | OPRM1 (0.41) | OPRL1OPRM1OPRK1OPRD1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198130-A | Liquid crystal mixtures | HOFFMANN-LA ROCHE INC. (US) | 1980-04-15 | — | — | US | disclosed |