Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3480757 | 0.91 | OPRM1 (0.41) | OPRM1OPRL1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL11364231 | 0.88 | OPRM1 (0.41) | OPRM1OPRL1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL11458352 | 0.85 | OPRL1 (0.46) | OPRM1OPRL1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL11466971 | 0.85 | OPRL1 (0.46) | OPRM1OPRL1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL11458351 | 0.85 | OPRL1 (0.46) | OPRM1OPRL1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL17072238 | 0.85 | OPRL1 (0.48) | OPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL11475337 | 0.84 | OPRL1 (0.49) | OPRM1OPRL1OPRK1OPRD1DRD2 | |
| SCHEMBL11457551 | 0.84 | OPRL1 (0.49) | OPRM1OPRL1OPRK1OPRD1DRD2 | |
| SCHEMBL11457550 | 0.84 | OPRL1 (0.49) | OPRM1OPRL1OPRK1OPRD1DRD2 | |
| SCHEMBL10893278 | 0.83 | OPRL1 (0.44) | OPRM1OPRL1OPRK1OPRD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119120038-A | Liquid crystal medium, liquid crystal display device containing same and compound | 默克专利股份有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-114144498-B | Liquid crystal medium, liquid crystal display device containing same and compound | 默克专利股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-110997871-B | Liquid crystal compound | 默克专利股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| US-11795398-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same and compounds | MERCK PATENT GMBH (DE) | 2023-10-24 | — | — | US | disclosed |
| US-11795398-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same and compounds | MERCK PATENT GMBH (DE) | 2023-10-24 | — | — | US | disclosed |
| EP-3994234-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS | Merck Patent GmbH (DE) | 2022-05-11 | — | — | EP | disclosed |
| CN-114144498-A | Liquid crystal medium, liquid crystal display containing same and compound | 默克专利股份有限公司 | 2022-03-04 | — | — | CN | disclosed |
| WO-2021004868-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS | MERCK PATENT GMBH (DE) | 2021-01-14 | — | — | WO | disclosed |
| CN-110997871-A | Liquid crystal compounds | 默克专利股份有限公司 | 2020-04-10 | — | — | CN | disclosed |
| WO-2019034588-A1 | LIQUID-CRYSTALLINE COMPOUNDS | MERCK PATENT GMBH (DE) | 2019-02-21 | — | — | WO | disclosed |
| WO-2019034588-A1 | LIQUID-CRYSTALLINE COMPOUNDS | MERCK PATENT GMBH (DE) | 2019-02-21 | — | — | WO | disclosed |
| EP-1897928-B1 | Chlorofluorobenzene liquid crystal compound, liquid crystal composition and liquid crystal display device | CHISSO CORP (JP) | 2010-10-27 | — | — | EP | disclosed |
| US-7695777-B2 | cyclohexenylene compounds which have a phenylene ring both fluoro and chloro substituted; wide temperature range; heat and light stable; small viscosity, large optical anisotropy; suitable negative dielectric anisotropy and excellent compatibility with other liquid crystal compounds; short response times | CHISSON CORPORATION (JP) | 2010-04-13 | — | — | US | disclosed |
| US-7695777-B2 | cyclohexenylene compounds which have a phenylene ring both fluoro and chloro substituted; wide temperature range; heat and light stable; small viscosity, large optical anisotropy; suitable negative dielectric anisotropy and excellent compatibility with other liquid crystal compounds; short response times | CHISSON CORPORATION (JP) | 2010-04-13 | — | — | US | disclosed |
| US-7695777-B2 | cyclohexenylene compounds which have a phenylene ring both fluoro and chloro substituted; wide temperature range; heat and light stable; small viscosity, large optical anisotropy; suitable negative dielectric anisotropy and excellent compatibility with other liquid crystal compounds; short response times | CHISSON CORPORATION (JP) | 2010-04-13 | — | — | US | disclosed |
| US-20080075891-A1 | cyclohexenylene compounds which have a phenylene ring both fluoro and chloro substituted; wide temperature range; heat and light stable; small viscosity, large optical anisotropy; suitable negative dielectric anisotropy and excellent compatibility with other liquid crystal compounds; short response times | CHISSO CORPORATION | 2008-03-27 | — | — | US | disclosed |
| US-20080075891-A1 | cyclohexenylene compounds which have a phenylene ring both fluoro and chloro substituted; wide temperature range; heat and light stable; small viscosity, large optical anisotropy; suitable negative dielectric anisotropy and excellent compatibility with other liquid crystal compounds; short response times | CHISSO CORPORATION | 2008-03-27 | — | — | US | disclosed |
| US-20080075891-A1 | cyclohexenylene compounds which have a phenylene ring both fluoro and chloro substituted; wide temperature range; heat and light stable; small viscosity, large optical anisotropy; suitable negative dielectric anisotropy and excellent compatibility with other liquid crystal compounds; short response times | CHISSO CORPORATION | 2008-03-27 | — | — | US | disclosed |
| EP-1897928-A1 | Chlorofluorobenzene liquid crystal compound, liquid crystal composition and liquid crystal display device | CHISSO CORPORATION (JP) | 2008-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080075891-A1 | cyclohexenylene compounds which have a phenylene ring both fluoro and chloro substituted; wide temperature range; heat and light stable; small viscosity, large optical anisotropy; suitable negative dielectric anisotropy and excellent compatibility with other liquid crystal compounds; short response times | CNKSR1, CLCN2, LEF1 | OPRM1 1117/4885OPRL1 2583/4885OPRK1 1031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.