Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 2/20 | 0.75 |
| ▸ | DRD4 | P21917 | 16/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Brl-20627 SCHEMBL9647317 | 0.86 | HTR4 (1.00) | HTR4DRD4DRD3DRD2 | |
| SCHEMBL10998621 | 0.86 | DRD4 (0.63) | HTR4DRD4DRD3 | |
| SCHEMBL11456486 | 0.85 | DRD4 (0.65) | HTR4DRD4 | |
| SCHEMBL9021444 | 0.85 | HTR4 (0.66) | HTR4DRD4DRD2 | |
| SCHEMBL9022232 | 0.84 | DRD4 (0.55) | HTR4DRD4DRD2 | |
| SCHEMBL9644709 | 0.81 | DRD4 (0.67) | HTR4DRD4 | |
| SCHEMBL9021909 | 0.81 | HTR4 (0.72) | HTR4DRD4 | |
| SCHEMBL9022207 | 0.80 | HTR4 (0.59) | HTR4DRD4DRD3DRD2 | |
| SCHEMBL9021711 | 0.80 | HTR4 (0.66) | HTR4DRD4 | |
| SCHEMBL16607301 | 0.79 | ALDH1A1 (0.64) | HTR4DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4213983-A | Treating gastro-intestinal disorders and emesis with n-(heterocyclic substituted) benzamides | BEECHAM GROUP LIMITED (GB) | 1980-07-22 | — | — | US | claimed |