Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11462249 | 0.79 | ITGB2 (0.35) | CYP3A4LMNAMAPT | |
| SCHEMBL11460809 | 0.79 | CA12 (0.44) | CYP3A4LMNA | |
| SCHEMBL6636617 | 0.79 | CA12 (0.44) | CYP3A4LMNA | |
| SCHEMBL11433922 | 0.76 | CA12 (0.48) | CYP3A4LMNA | |
| SCHEMBL11460819 | 0.76 | CA12 (0.48) | CYP3A4LMNA | |
| SCHEMBL20376283 | 0.74 | MAPT (0.32) | LMNAMAPT | |
| SCHEMBL25132091 | 0.74 | CA1 (0.34) | CYP3A4LMNA | |
| SCHEMBL104712 | 0.73 | NPC1 (0.48) | CYP3A4LMNA | |
| SCHEMBL104713 | 0.73 | NPC1 (0.48) | CYP3A4LMNA | |
| SCHEMBL11144149 | 0.71 | ZDHHC20 (0.38) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4209446-A | FROM PIPERONAL AND A CROTONIC AMIDE IN PRESENCE OF ALKALI METAL HYDROXIDE AND DIPOLAR APROTIC DILUENT | HAARMAN & REIMER GMBH (DE) | 1980-06-24 | — | — | US | disclosed |
| US-4209445-A | FROM PIPERONAL AND A CROTONIC AMIDE IN PRESENCE OF QUATERNARY AMMONIUM OR PHOSPHONIUM HYDROXIDE OR CROWN ETHER METAL COMPLEX | HAARMAN & REIMER GMBH (DE) | 1980-06-24 | — | — | US | disclosed |