Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104712 | 1.00 | NPC1 (0.48) | NPC1L3MBTL1CYP3A4LMNATRPM8 | |
| SCHEMBL9113596 | 0.86 | CA12 (0.41) | NPC1L3MBTL1CYP3A4LMNAPSMB5 | |
| SCHEMBL1395649 | 0.86 | NPC1 (0.54) | NPC1L3MBTL1CYP3A4LMNATRPM8 | |
| SCHEMBL1630772 | 0.86 | NPC1 (0.54) | NPC1L3MBTL1CYP3A4LMNATRPM8 | |
| SCHEMBL1022195 | 0.86 | NPC1 (0.54) | NPC1L3MBTL1CYP3A4LMNATRPM8 | |
| SCHEMBL280608 | 0.84 | NPC1 (0.38) | NPC1L3MBTL1CYP3A4LMNATRPM8 | |
| SCHEMBL17666080 | 0.84 | NPC1 (0.42) | NPC1L3MBTL1CYP3A4LMNATRPM8 | |
| SCHEMBL17666075 | 0.84 | NPC1 (0.42) | NPC1L3MBTL1CYP3A4LMNATRPM8 | |
| SCHEMBL9030004 | 0.83 | NPC1 (0.44) | NPC1L3MBTL1CYP3A4LMNATRPM8 | |
| SCHEMBL9030008 | 0.83 | NPC1 (0.44) | NPC1L3MBTL1CYP3A4LMNATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218507-B | 1, 3, 6, 7-tetrahydroxy xanthone derivative and preparation method and application thereof | 中国药科大学 | 2020-10-02 | — | — | CN | claimed |
| US-5858592-A | STOPS CHARGE INJECTION FROM SURFACE AND STABILIZES DARK DECAY; ALLOWS ELECTRON TRANSFER/TRANSPORT TO EFFECTIVELY NEUTRALIZE SURFACE CHARGE; CONTROLS POLYMER CHAIN MOVEMENT PHENOMENA | HEWLETT-PACKARD COMPANY (US) | 1999-01-12 | — | — | US | claimed |
| US-4588833-A | CARBON MONOXIDE, ALCOHOL OR AMINE, ACID, UNSATURATED AMIDE, COBALTCOMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-13 | — | — | US | claimed |
| CN-116135861-A | Method for preparing boronated carbonyl derivative from alpha, beta-unsaturated carbonyl derivative | 中国科学院大连化学物理研究所 | 2023-05-19 | — | — | CN | disclosed |
| CN-114163581-A | Concrete tackifier and preparation method thereof | 安徽海螺新材料科技有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-105218507-B | 1, 3, 6, 7-tetrahydroxy xanthone derivative and preparation method and application thereof | 中国药科大学 | 2020-10-02 | — | — | CN | disclosed |
| CN-105101935-B | Curable composition | 可乐丽则武齿科株式会社 | 2018-02-23 | — | — | CN | disclosed |
| US-20150225332-A1 | METHOD FOR PRODUCING ALPHA,BETA-UNSATURATED CARBOXYLIC ACID-N,N-DISUBSTITUTED AMIDE AND METHOD FOR PRODUCING 3-ALKOXYCARBOXYLIC ACID-N,N-DISUBSTITUTED AMIDE | IDEMITSU KOSAN CO., LTD. (JP) | 2015-08-13 | — | — | US | disclosed |
| US-20140235894-A1 | METHOD FOR PRODUCING ALPHA,BETA-UNSATURATED CARBOXYLIC ACID-N,N-DISUBSTITUTED AMIDE AND METHOD FOR PRODUCING 3-ALKOXYCARBOXYLIC ACID-N,N-DISUBSTITUTED AMIDE | IDEMITSU KOSAN CO., LTD. (JP) | 2014-08-21 | — | — | US | disclosed |
| US-8748659-B2 | Method for producing alpha,beta-unsaturated carboxylic acid-N,N-disubstituted amide and method for producing 3-alkoxycarboxylic acid-N,N-disubstituted amide | IDEMITSU KOSAN CO., LTD. (JP) | 2014-06-10 | — | — | US | disclosed |
| EP-2664610-A1 | Method for producing alpha,beta-unsaturated carboxylic acid-N,N-disubstituted amide and method for producing 3-alkoxycarboxylic acid-N,N-disubstituted amide | Idemitsu Kosan Co., Ltd (JP) | 2013-11-20 | — | — | EP | disclosed |
| US-4306949-A | WHEREIN A GAS IS INTRODUCED TO DILUTE THE OXYGEN CONCENTRATION AND PREVENT CORROSION OF THE CATHODE | MONSANTO COMPANY (US) | 1981-12-22 | — | — | US | disclosed |
| US-4209445-A | FROM PIPERONAL AND A CROTONIC AMIDE IN PRESENCE OF QUATERNARY AMMONIUM OR PHOSPHONIUM HYDROXIDE OR CROWN ETHER METAL COMPLEX | HAARMAN & REIMER GMBH (DE) | 1980-06-24 | — | — | US | disclosed |
| US-4209446-A | FROM PIPERONAL AND A CROTONIC AMIDE IN PRESENCE OF ALKALI METAL HYDROXIDE AND DIPOLAR APROTIC DILUENT | HAARMAN & REIMER GMBH (DE) | 1980-06-24 | — | — | US | disclosed |
| US-4207151-A | Electrohydrodimerization process improvement and improved electrolyte recovery process | MONSANTO COMPANY (US) | 1980-06-10 | — | — | US | disclosed |
| US-4144388-A | Film-forming and thermocurable vinyl alcohol-substituted acrylamide copolymers and process for production thereof | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-13 | — | — | US | disclosed |
| US-4028201-A | Electrolytic monocarboxylation of activated olefins | MONSANTO COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-4013524-A | Electrolytic carboxylation and dimerization of olefins | MONSANTO COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
| US-3966566-A | Electrolytic hydrodimerization process improvement | MONSANTO COMPANY (US) | 1976-06-29 | — | — | US | disclosed |
| US-3960679-A | Process for hydrodimerizing olefinic compounds | MONSANTO COMPANY (US) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225332-A1 | METHOD FOR PRODUCING ALPHA,BETA-UNSATURATED CARBOXYLIC ACID-N,N-DISUBSTITUTED AMIDE AND METHOD FOR PRODUCING 3-ALKOXYCARBOXYLIC ACID-N,N-DISUBSTITUTED AMIDE | FASN, NAAA, FAAH | NPC1 478/4885L3MBTL1 4475/4885CYP3A4 1784/4885 |
| US-20140235894-A1 | METHOD FOR PRODUCING ALPHA,BETA-UNSATURATED CARBOXYLIC ACID-N,N-DISUBSTITUTED AMIDE AND METHOD FOR PRODUCING 3-ALKOXYCARBOXYLIC ACID-N,N-DISUBSTITUTED AMIDE | FASN, NAAA, FAAH | NPC1 478/4885L3MBTL1 4475/4885CYP3A4 1784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.