Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 3/20 | 0.34 |
| ▸ | GSK3B | P49841 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11458770 | 0.80 | POLB (0.34) | POLBMAPTGSK3AGSK3BMEN1 | |
| SCHEMBL11458769 | 0.77 | POLB (0.36) | POLBMAPTGSK3AGSK3B | |
| SCHEMBL11460468 | 0.75 | POLB (0.34) | POLBMAPT | |
| SCHEMBL11460834 | 0.74 | POLB (0.33) | POLBMAPT | |
| SCHEMBL11469181 | 0.73 | FAAH (0.33) | POLBMAPT | |
| SCHEMBL10620209 | 0.72 | — | — | |
| SCHEMBL14598683 | 0.68 | POLB (0.40) | POLBMAPTGSK3AGSK3BMEN1 | |
| SCHEMBL11462021 | 0.67 | — | — | |
| SCHEMBL11469305 | 0.64 | ALDH1A1 (0.46) | MAPTALDH1A1HSD17B10 | |
| SCHEMBL11384228 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4207236-A | 3-(tert-Alkylthio)-1,3-thiazolidin-2,4-dione | MONSANTO COMPANY (US) | 1980-06-10 | — | — | US | disclosed |
| US-4207236-A | 3-(tert-Alkylthio)-1,3-thiazolidin-2,4-dione | MONSANTO COMPANY (US) | 1980-06-10 | — | — | US | disclosed |
| US-4165417-A | 3-(Tert-alkylthio)-1,3-thiazolidin-2,4-dione used to inhibit premature vulcanization of diene rubbers | MONSANTO COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| US-4165417-A | 3-(Tert-alkylthio)-1,3-thiazolidin-2,4-dione used to inhibit premature vulcanization of diene rubbers | MONSANTO COMPANY (US) | 1979-08-21 | — | — | US | disclosed |