Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 6/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099351 | 0.87 | CYP2C19 (0.43) | CYP2C19CYP2D6LMNACYP3A4CYP1A2 | |
| SCHEMBL11460548 | 0.85 | LMNA (0.42) | CYP2C19CYP2D6LMNACYP3A4CYP1A2 | |
| SCHEMBL11315628 | 0.81 | CYP2C19 (0.48) | CYP2C19CYP2D6LMNACYP3A4CYP1A2 | |
| SCHEMBL11768030 | 0.80 | GRIK1 (0.39) | CYP2C19CYP2D6LMNACYP3A4CYP1A2 | |
| SCHEMBL11770543 | 0.80 | GRIK1 (0.39) | CYP2C19CYP2D6LMNACYP3A4CYP1A2 | |
| SCHEMBL11662216 | 0.79 | GLRA3 (0.43) | CYP2C19CYP2D6LMNACYP3A4CYP1A2 | |
| Hydrochloric Acid SCHEMBL11337216 | 0.79 | LMNA (0.49) | CYP2C19CYP2D6LMNACYP3A4CYP1A2 | |
| SCHEMBL11099358 | 0.79 | CYP2C19 (0.41) | CYP2C19CYP2D6LMNACYP3A4CYP1A2 | |
| SCHEMBL11487244 | 0.78 | HMGCR (0.51) | CYP2C19CYP2D6LMNACYP3A4CYP1A2 | |
| SCHEMBL11464540 | 0.78 | ESR1 (0.45) | CYP2C19CYP2D6LMNACYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4196301-A | STABILIZERS, OXIDATION AND HEAT RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1980-04-01 | — | — | US | disclosed |
| US-4187246-A | HEAT AND LIGHT STABILIZERS FOR POLYOLEFINS | CIBA-GEIGY CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |
| US-4093618-A | STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |
| US-4075161-A | STABILIZERS FOR POLYOLEFINS | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |
| US-3988363-A | STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |