Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL28344769 | 0.82 | CYP2C19 (0.39) | CYP2C19LMNACYP3A4HTR1AADRA2A | |
| SCHEMBL7525281 | 0.79 | ALDH1A1 (0.44) | CYP2C19LMNACYP3A4CYP1A2CYP2D6 | |
| SCHEMBL11468012 | 0.79 | CYP2C19 (0.46) | CYP2C19LMNACYP3A4HTR1AADRA2A | |
| SCHEMBL11099349 | 0.78 | CYP2C19 (0.43) | CYP2C19LMNACYP3A4HTR1AADRA2A | |
| SCHEMBL6446000 | 0.78 | CYP2C19 (0.50) | CYP2C19LMNACYP3A4HTR1AADRA2A | |
| SCHEMBL10818867 | 0.78 | CYP2C19 (0.50) | CYP2C19LMNACYP3A4HTR1AADRA2A | |
| SCHEMBL29395885 | 0.78 | CYP2C19 (0.50) | CYP2C19LMNACYP3A4HTR1AADRA2A | |
| SCHEMBL1250827 | 0.75 | CYP2C19 (0.37) | CYP2C19LMNACYP3A4HTR1AADRA2A | |
| SCHEMBL11315628 | 0.75 | CYP2C19 (0.48) | CYP2C19LMNACYP3A4HTR1AADRA2A | |
| SCHEMBL11099351 | 0.75 | CYP2C19 (0.43) | CYP2C19LMNACYP3A4HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439615-A | ANTIOXIDANTS | CIBA-GEIGY CORPORATION (US) | 1984-03-27 | — | — | US | disclosed |