Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.53 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | HMGCR | P04035 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | EEF2K | O00418 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964070 | 0.84 | GABBR2 (0.59) | GABBR2GABBR1PTGS1PTGS2CYP1A2 | |
| SCHEMBL8072535 | 0.80 | GABBR2 (0.58) | GABBR2GABBR1PTGS1PTGS2CYP1A2 | |
| SCHEMBL8072537 | 0.80 | GABBR2 (0.58) | GABBR2GABBR1PTGS1PTGS2CYP1A2 | |
| SCHEMBL10031552 | 0.78 | GABBR2 (0.64) | GABBR2GABBR1PTGS1PTGS2CYP1A2 | |
| SCHEMBL31375211 | 0.76 | GABBR2 (0.58) | GABBR2GABBR1PTGS1PTGS2CYP1A2 | |
| SCHEMBL1821480 | 0.75 | PTGS1 (0.74) | GABBR2GABBR1PTGS1PTGS2CYP1A2 | |
| SCHEMBL1821479 | 0.75 | PTGS1 (0.74) | GABBR2GABBR1PTGS1PTGS2CYP1A2 | |
| SCHEMBL9307857 | 0.75 | GABBR2 (0.56) | GABBR2GABBR1PTGS1PTGS2CYP1A2 | |
| SCHEMBL9307852 | 0.75 | GABBR2 (0.56) | GABBR2GABBR1PTGS1PTGS2CYP1A2 | |
| SCHEMBL4450572 | 0.73 | GABBR2 (0.68) | GABBR2GABBR1PTGS1PTGS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202816-A | ENOL-PIPERIDINE METAL COMPLEXES | CIBA-GEIGY CORPORATION (US) | 1980-05-13 | — | — | US | disclosed |