Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11472434 | 0.93 | LMNA (0.44) | LMNAALDH1A1ADORA3OPRM1CYP3A4 | |
| SCHEMBL11476138 | 0.89 | HTR7 (0.42) | LMNAALDH1A1OPRM1CA1CA2 | |
| SCHEMBL11159584 | 0.89 | LMNA (0.53) | LMNAALDH1A1ADORA3OPRM1CYP3A4 | |
| SCHEMBL11662844 | 0.80 | LMNA (0.47) | LMNAADORA3MDM2CRHR1BRD4 | |
| SCHEMBL11477721 | 0.80 | LMNA (0.43) | LMNAALDH1A1OPRM1CYP3A4CYP2D6 | |
| SCHEMBL11481275 | 0.80 | LMNA (0.53) | LMNAALDH1A1ADORA3OPRM1CYP3A4 | |
| SCHEMBL11468063 | 0.79 | PDE6D (0.42) | LMNAALDH1A1OPRM1TSHRCYP3A4 | |
| SCHEMBL11163109 | 0.76 | LMNA (0.42) | LMNAALDH1A1OPRM1CA1CA2 | |
| SCHEMBL11479612 | 0.73 | LMNA (0.53) | LMNAALDH1A1ADORA3TSHRBRD4 | |
| SCHEMBL11724230 | 0.72 | LMNA (0.41) | LMNAALDH1A1ADORA3CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202974-A | Process for preparing 3,4-dihydro-2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-05-13 | — | — | US | disclosed |