Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | CCR8 | P51685 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.41 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20125014 | 0.82 | MAPT (0.51) | AHRKDM4ETDP1FLT3L3MBTL1 | |
| SCHEMBL15828604 | 0.78 | KDM4E (0.42) | AHRKDM4ETDP1L3MBTL1TP53 | |
| SCHEMBL10799076 | 0.78 | KDM4E (0.52) | KDM4ETDP1L3MBTL1CCR1CCR5 | |
| SCHEMBL4021715 | 0.74 | CCR1 (0.45) | KDM4ETDP1FLT3L3MBTL1CCR1 | |
| SCHEMBL11012484 | 0.72 | RAB9A (0.64) | KDM4ETDP1FLT3L3MBTL1CCR1 | |
| SCHEMBL15937966 | 0.72 | AHR (0.58) | AHRKDM4EGAATP53MAPT | |
| SCHEMBL11483589 | 0.69 | HTT (0.47) | KDM4ETDP1GRM5GAATP53 | |
| SCHEMBL10987450 | 0.68 | KDM4E (0.52) | KDM4ETDP1L3MBTL1CCR1CCR5 | |
| SCHEMBL13750598 | 0.68 | KDM4E (0.46) | KDM4ETDP1FLT3L3MBTL1CCR1 | |
| SCHEMBL15415685 | 0.66 | AHR (0.51) | AHRKDM4EL3MBTL1GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4183741-A | POSTEMERGENCE | FISONS LIMITED (GB) | 1980-01-15 | — | — | US | disclosed |